52 citations
,
October 1995 in “Experimental Cell Research” Human hair keratin genes hHa2 and hHb1 are located on chromosomes 17 and 12.
28 citations
,
September 1995 in “Biochemistry and Cell Biology” Merkel cells are more densely found in hairless skin areas like palms and soles.
38 citations
,
February 1989 in “Journal of Investigative Dermatology”
1 citations
,
December 2024 in “Methods in molecular biology” Hair proteins are complex and provide valuable genetic and biological information.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
8 citations
,
July 2011 in “Animal science journal” Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
72 citations
,
May 1993 in “The Journal of Cell Biology” Trichohyalin in sheep hair follicles may help with structure and calcium binding.
29 citations
,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
47 citations
,
July 1997 in “British Journal of Dermatology” The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
7 citations
,
February 1998 in “Polymer journal” Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
5 citations
,
March 1943 in “Archives of Dermatology and Syphilology” A rare case of severe scalp hair loss and nail issues in keratosis follicularis was observed.
3 citations
,
September 2013 in “Bioscience Biotechnology and Biochemistry” Type II porcine hair keratin supports cell growth but hinders cell differentiation.
45 citations
,
February 2013 in “The Journal of Dermatology” Keratoacanthoma and some squamous cell carcinomas are linked to hair follicles, while others are not.
427 citations
,
April 2008 in “Nature Protocols” 67 citations
,
December 1990 in “The journal of cell biology/The Journal of cell biology” Researchers found genes for cysteine-rich proteins that form the protective layer of hair in humans and sheep.
February 2023 in “European biophysics journal” 28 citations
,
November 2009 in “Journal of Structural Biology” High flux X-ray beams quickly damage the structure of human hair.
42 citations
,
September 1985 in “British Journal of Dermatology” Trichothiodystrophy causes abnormal protein deposits and distortion in hair follicles.
The naked mutation in mice causes hair loss and helps identify keratin genes.
April 2018 in “Journal of Investigative Dermatology” Basonuclin 1 (BNC1) helps skin cells multiply and move, which is crucial for wound healing.
62 citations
,
October 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes can change hair structure and cause monilethrix, with nail issues more common in certain gene mutations.
January 2003 in “Jiepouxue zazhi” HHK can help restore skin structure.
17 citations
,
January 2016 in “Journal of Drug Delivery” PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
March 2026 in “Experimental Dermatology” The new model helps understand and develop treatments for genetic skin disorders like AEC.
August 2023 in “Drug Delivery and Translational Research” Human hair keratin was used to create a scaffold that could help with skin repair.
27 citations
,
April 2018 in “Artificial Cells Nanomedicine and Biotechnology” Recombinant human hair keratin proteins can effectively stop bleeding.
1 citations
,
March 1991 in “PubMed” Naevoid bundle hair is an unusual hair growth pattern where multiple hairs fuse together.
2 citations
,
May 2022 in “Research Square (Research Square)” KGF-1 135 is a stable and effective alternative for treating oral mucositis.
August 2019 in “Journal of Investigative Dermatology” The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.