research Role of neurosteroids in the anticonvulsant activity of midazolam
Midazolam's seizure prevention is partly due to increased neurosteroid production.
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research A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology
Hibiscus rosa-sinensis is used in traditional medicine and is safe in high doses, with various health benefits.
research Prefrontal 5α-reductase 2 mediates male-specific acute stress response
5α-reductase 2 is crucial for stress response in male rats.
research Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.
research Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol
Testosterone increases seizure risk through its conversion to specific neurosteroids.
research Alterations in neonatal neurosteroids affect exploration during adolescence and prepulse inhibition in adulthood
Early-life neurosteroid changes affect adolescent exploration and adult behavior.
research Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice
GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
research Antioxidant activity of various solvent extracts from endophytic bacteria isolated from girang (Leea indica) leaves
Bacillus tequilensis from Leea indica leaves is a strong natural antioxidant source.
research New Insights into the Research of Bioactive Compounds from Plant Origins with Nutraceutical and Pharmaceutical Potential
Plant bioactive compounds are important for health and can help prevent various diseases.
research Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis.
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research Repurposing Finasteride and Serotonin Reuptake Inhibitors as Novel Antimicrobials: A Dual-Action Approach to Target Bacterial and Fungal Pathogens
Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.
research Neurosteroids as Endogenous Regulators of Seizure Susceptibility
Stress increases neurosteroids that help prevent seizures.
research Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health
Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
research The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches
Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.
research Role of Phenylalanine and Its Metabolites in Health and Neurological Disorders
Phenylalanine may help with depression but can cause issues if not properly processed.
research Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.
research Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats
Neonatal neurosteroid levels affect adult brain function and behavior.
research Subcellular localization of the five members of the human steroid 5α-reductase family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease
New compounds may help treat heart disease by activating specific potassium channels.
research A Clinical Evaluation of Guduchi (Tinospora cordifolia) and Yashtimadhu (Glycyrrhiza glabra) as Chemopreventive Agent in Cancer Treatment
Guduchi and Yashtimadhu can reduce chemotherapy side effects.
research Clinical and pathological evaluation of hemp seeds oil effectiveness in the treatment of alopecia areata
Hemp seed oil shows promise in treating localized alopecia areata.
research Early post-natal neuroactive steroid manipulation modulates ondansetron effects on initial periods of alcohol consumption in rats
Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
research Hair Growth Promotion by δ-Opioid Receptor Activation
Activating δ-opioid receptors can help hair grow.
research The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration
Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
research Systematic Evaluation of Rosemary Essential Oil in Aromatherapy Practice: A Review
Rosemary essential oil can improve mood, sleep, and cognitive function but may cause allergies, so use it carefully.
research Therapeutic potential of extracellular vesicles derived from Platycladus Orientalis leaf in treating anxiety, depression, and insomnia
Platycladus Orientalis leaf vesicles may help treat anxiety, depression, and insomnia.
research Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases
Finasteride use is linked to a higher risk of memory problems.
research How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research The effect of finasteride on anxiety in rats
Finasteride may increase anxiety in bright spaces.
research Ethnodermatological use of medicinal plants in India: From ayurvedic formulations to clinical perspectives – A review
Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.