January 2026 in “Cronfa (Swansea University)” Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
July 1997 in “The Lancet” Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
112 citations
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July 2012 in “The Journal of Sexual Medicine” Finasteride may cause long-lasting sexual side effects.
10 citations
,
October 2010 in “International Journal of Andrology” Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
9 citations
,
January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
June 2019 in “Journal of Drug Delivery and Therapeutics” Finasteride effectively treats hair loss and prostate issues with minimal side effects.
July 2007 in “Journal of Reproduction & Infertility” Short-term finasteride use likely doesn't harm male fertility.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
64 citations
,
June 2009 in “Journal of The American Academy of Dermatology” Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.
March 2016 in “Reactions Weekly” Post-finasteride syndrome causes various symptoms in men using finasteride, with no known cure.
4 citations
,
December 2013 in “Archivio italiano di urologia, andrologia” Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.
Finasteride may reduce heart damage in rats.
May 2017 in “Journal of The American Academy of Dermatology” Finasteride and dutasteride increase sexual dysfunction reports.
January 2025 in “Thieme Medical and Scientific Publishers Private Limited eBooks”
15 citations
,
June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
1 citations
,
May 1998 in “Inpharma Weekly” Finasteride works for male hair loss only.
5 citations
,
January 2018 in “Research Journal of Pharmacy and Technology” Finasteride significantly reduces fertility in male rats.
January 2018 in “International Journal of Medical Research and Health Sciences” Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.
11 citations
,
April 2018 in “Journal of Dermatology” Dutasteride safely treats hair loss without harming sexual function.
June 2025 in “Reactions Weekly” Finasteride may increase the risk of depression and suicidal thoughts.
January 2011 in “Shandong yiyao” Finasteride reduces bleeding during prostate surgery.
November 2025 in “Australian Journal of General Practice” Oral finasteride and topical minoxidil can regrow hair, but finasteride may affect fertility.
December 2025 in “Instituto Politécnico do Porto” Patients with mood disorders using 5α-reductase inhibitors may have a higher risk of suicidal thoughts.
17 citations
,
September 2020 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
1 citations
,
January 2023 in “Drug Development and Industrial Pharmacy” DMSO-liposomes improve finasteride delivery for hair loss treatment.
June 2026 in “Pharmaceuticals” 5α-Reductase inhibitors, like finasteride, can cause serious, persistent side effects not always listed in official drug information.
34 citations
,
February 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and minoxidil together promote hair growth better than either alone.
March 2005 in “European Urology Supplements”
October 2025 in “Frontiers in Medicine” The minoxidil-finasteride combination is more effective for hair growth than minoxidil alone.