126 citations
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January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
103 citations
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June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
98 citations
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February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
97 citations
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March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
91 citations
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December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
90 citations
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October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
76 citations
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April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
74 citations
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September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
70 citations
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July 2020 in “Pharmacological Reports” Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
67 citations
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May 2018 in “Journal of Ginseng Research” Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
66 citations
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February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
64 citations
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January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
58 citations
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January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
56 citations
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February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
54 citations
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April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
54 citations
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November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
54 citations
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December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
53 citations
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September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
53 citations
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November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
51 citations
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November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
49 citations
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November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
49 citations
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April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
49 citations
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December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
49 citations
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April 2006 in “Journal of Investigative Dermatology” TRPV1 helps regulate hair growth cycles.
48 citations
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January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
47 citations
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February 2015 in “European Journal of Clinical Investigation” The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
47 citations
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January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
44 citations
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March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.