April 2021 in “Arab Journal of Nuclear Sciences and Applications/Arab Journal of Nuclear Sciences and Applications ” Repeated use of protein hair conditioner with heat or gamma irradiation can harm skin and hair health in rats.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
95 citations
,
January 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
4 citations
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November 2015 in “Journal of Investigative Dermatology” Testosterone may worsen hair loss by affecting hair growth signals, while different prostaglandins can either hinder or promote hair growth.
May 2019 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Frontal fibrosing alopecia mostly affects postmenopausal women, with diagnosis often delayed by 3 years.
October 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” Variegated coat color in cats is linked to the Silver locus.
January 2015 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” Men with severe hair loss may have a higher risk of heart disease.
13 citations
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May 2021 in “Plants” The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.
5 citations
,
September 2022 in “Research Square (Research Square)” CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
35 citations
,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
555 citations
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July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
144 citations
,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
123 citations
,
November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
108 citations
,
February 2008 in “The Journal of urology/The journal of urology” Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
70 citations
,
December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
66 citations
,
August 2011 in “Parasitology Research” Mint essential oils can kill parasites that cause cystic echinococcosis, with M. pulegium oil being more effective than M. piperita oil.
65 citations
,
September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
60 citations
,
January 2023 in “Biogerontology” Adequate testosterone is crucial for men's health and quality of life, but its decline with age needs more research.
52 citations
,
October 2010 in “Antiviral Therapy” New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
49 citations
,
January 2018 in “Theranostics” The new skin patch with human matrix and antibiotic improves wound healing.
47 citations
,
January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
46 citations
,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
46 citations
,
December 1992 in “Journal of Investigative Dermatology” Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
45 citations
,
August 2011 in “Journal of Microencapsulation” Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
44 citations
,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
41 citations
,
March 2017 in “PLoS neglected tropical diseases” Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
33 citations
,
February 2021 in “Advanced Pharmaceutical Bulletin” Transdermal drug delivery systems are effective and promising for future use.