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Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair cells.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Ritlecitinib effectively regrows scalp, eyebrow, and eyelash hair in Asians with alopecia areata and is safe.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Switching to ritlecitinib improves hair regrowth and well-being in severe alopecia areata patients.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

AMPK activation may reduce melanoma risk in red-haired individuals.

A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.

The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

β-sitosterol and brassicasterol may help treat hair loss.

Oral 5-alpha-reductase inhibitors for hair loss don't increase heart risk.

AQB reduces harmful skin changes in systemic sclerosis.

5α-reductase inhibitors help manage symptoms of benign prostatic hyperplasia and may also prevent prostate cancer and treat hair loss.

Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.

Dutasteride may reduce insulin sensitivity and increase body fat.

Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.

Ritlecitinib effectively improves hair growth in alopecia areata patients, regardless of hair loss pattern.

Ritlecitinib is more effective and cheaper than baricitinib for treating severe alopecia areata.