September 2025 in “International Journal of Innovative Technologies in Social Science” Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.
January 2007 in “xPharm: The Comprehensive Pharmacology Reference” 1 citations
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September 1981 in “PubMed” Cyproterone acetate effectively treats virilized women, especially under 35, despite some side effects.
27 citations
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October 1991 in “International journal of gynaecology and obstetrics” Flutamide effectively reduces hair growth in women with hirsutism and improves acne and seborrhea without side effects.
16 citations
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October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
November 2025 in “JAAD Case Reports” Oral dutasteride, minoxidil, and finasteride may help reduce hair loss in breast cancer survivors, but more research is needed.
May 2024 in “Reactions weekly”
January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
5α-reductase inhibitors help treat prostate enlargement and hair loss but may cause side effects, requiring careful use.
The combination of high-dose toremifene and capecitabine was effective for advanced recurrent breast cancer.
67 citations
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April 2018 in “JAMA Dermatology” Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.
4 citations
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November 2021 in “Journal of The American Academy of Dermatology” Bicalutamide may reduce unwanted hair growth caused by minoxidil in women with hair loss.
3 citations
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November 2013 in “PubMed”
December 2025 in “Clinical & Experimental Dermatology and Therapies” Cosmerna ARI effectively reduces hair loss and increases hair density in Europeans with androgenetic alopecia.
6 citations
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September 2024 in “Journal of the American Academy of Dermatology” Oral 5-alpha reductase inhibitors do not increase breast cancer or benign breast disorder risk in women.
14 citations
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November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
January 2025 in “Journal of Prescribing Practice” 5 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” Nuclear AR levels give better insight into hormone effects in skin conditions.
December 2025 in “Cureus” Using 5α-reductase inhibitors for hair loss may increase the risk of dry eye disease.
January 2007 in “日本看護学会抄録集 成人看護1” Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.
25 citations
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June 2002 in “Steroids” 4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
April 2024 in “Expert opinion on emerging drugs” New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
13 citations
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January 2017 in “Chemical & Pharmaceutical Bulletin” Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
4 citations
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October 2018 in “International Braz J Urol” Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.
July 2024 in “Age and Ageing” Men taking dutasteride may have a higher risk of age-related macular degeneration.
February 2026 in “Revista Eletrônica Polidisciplinar Voos.” A balanced approach using dutasteride and Serenoa repens can improve hair transplant success by protecting follicles and minimizing side effects.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
2 citations
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February 2003 in “Obstetrical & Gynecological Survey” Most antiandrogen treatments effectively reduce acne in hyperandrogenic women, but finasteride is the least effective.