May 2023 in “Clinical and Experimental Dermatology” Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.
July 2018 in “Elsevier eBooks” Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
September 2017 in “PubMed” Monilethrix is a rare genetic hair disorder with no cure, but low-dose oral minoxidil may help.
December 2010 in “Elsevier eBooks” Systemic lupus erythematosus is an autoimmune disease causing diverse symptoms and major organ involvement.
3 citations
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December 2010 in “Annals of tropical paediatrics” A boy's hair loss and bone issues improved with specific vitamin D treatment and calcium.
December 2025 in “Cureus” Early diagnosis and treatment of calcinosis cutis in lupus patients is crucial due to its rarity and potential complications.
3 citations
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September 2021 in “JAAD case reports” Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.
110 citations
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November 1984 in “The American Journal of Medicine” A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.
3 citations
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January 2013 in “Türk veterinerlik ve hayvancılık dergisi/Turkish journal of veterinary and animal sciences” A cat in Turkey had Ehlers-Danlos syndrome, showing very stretchy skin and easy bruising.
2 citations
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September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Tissue stiffness is influenced by contractility, which suppresses collagen breakdown.
4 citations
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August 2005 in “Clinical Infectious Diseases” The man's symptoms improved after treating his scurvy with high-dose vitamin C.
November 2025 in “Practical Neurology” Correct diagnosis and treatment of lupus vasculitis improved the woman's severe symptoms.
3 citations
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March 2017 in “Case Reports in Dermatology” A woman with lupus improved significantly from scalp hair loss after treatment, highlighting the need to identify psoriatic alopecia in lupus patients to avoid permanent hair loss.
April 2023 in “Nigerian Journal of Clinical Practice” Hair loss in adults is linked to heart disease risk factors like unhealthy blood fats, lack of exercise, and alcohol use. It's also slightly more common in people with metabolic syndrome. As people age, hair loss gets worse. In men, severe hair loss is tied to high blood pressure and a larger waist. In women, it's tied to higher body weight. People with hair loss should be checked for unhealthy blood fats and advised to avoid alcohol and inactivity.
August 2018 in “Journal of The American Academy of Dermatology” Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.
May 2022 in “Experimental dermatology” Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
June 2009 in “Mayo Clinic Proceedings” A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.
October 2024 in “Dermatology Practical & Conceptual” Porokeratosis should be considered for scalp lesions, with new treatments like topical cholesterol/lovastatin offering promise.
1 citations
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January 2017 in “SAGE Open Medical Case Reports” A woman's hair loss condition got worse after her varicose vein treatment with a specific foam.
January 2023 in “Indian dermatology online journal” Skin problems after waxing led to a sarcoidosis diagnosis.
October 2024 in “Skin Research and Technology” Pili annulati causes zebra-striped hair but doesn't affect hair strength or quality of life.
158 citations
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February 2000 in “Archives of dermatology” Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
June 2025 in “British Journal of Dermatology” Premature canities is linked to low vitamin D and B12, family history, and higher MHR.
35 citations
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January 2002 in “Dermatology” A woman's hair loss during treatment with specific hepatitis C drugs grew back after stopping the medication.
26 citations
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January 1983 in “PubMed” Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.
March 2025 in “Journal of Cosmetic Dermatology” Botulinum toxin type A may widen certain arteries, but more research is needed.
11 citations
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January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” A 4-year-old boy with a rare type of rickets and hair loss improved in bone health but not hair growth after vitamin D and calcium treatment.
May 2024 in “Frontiers in medicine” A genetic mutation in the LIPH gene causes tightly curled hair that stops growing in some Japanese individuals.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
Higher disease activity in systemic lupus erythematosus is strongly linked to more internal organ damage.