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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

The most common cause of hair loss in children is tinea capitis, followed by alopecia areata and telogen effluvium.

Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.

NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.

Many patients in the rheumatology clinic adjusted or stopped their medications due to side effects.

Pregnant women with Systemic Lupus Erythematosus have a higher risk of blood clotting problems.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

The CRH/CRH-R1 system might be involved in causing lichen planus.

Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.

Lichen planus may be associated with a higher risk of metabolic syndrome.

A woman with severe hair loss due to systemic sclerosis regrew her hair in 4 months using a combination of treatments.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.

Folate may reduce methotrexate side effects in psoriasis patients, but its impact on effectiveness is unclear.

New research is helping develop better treatments for alopecia areata.

A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.

Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.

Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.

Clofazimine effectively treated ashy dermatosis in a patient.

Clofazimine may be effective for treating ashy dermatosis.

People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.

Clofazimine successfully treated a man's ashy dermatosis, clearing his skin lesions.

A woman's psoriasis improved after hepatitis C treatment with interferon, despite interferon's risk of worsening skin conditions.

Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Older people often have untreated genital skin diseases due to embarrassment and lack of medical attention, which can lead to discomfort and even cancer risk.

Aging affects hair density and skin health, and Behcet's disease, a complex condition with no specific test, involves sores and systemic issues, treated with various medications.