155 citations
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March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
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January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
July 1998 in “Annals of saudi medicine/Annals of Saudi medicine” A misdiagnosed case of HAIR-AN syndrome led to unnecessary surgeries and highlighted the importance of correct diagnosis and treatment.
January 2000 in “Alambique: Didáctica de las ciencias experimentales” Cholesterol issues in skin and hair may cause permanent hair loss by triggering inflammation.
March 2025 in “JAAD International” Alopecia areata is rare in organ transplant patients and may be linked to the drug tacrolimus.
109 citations
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May 2011 in “Dermatologic Therapy” Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.
23 citations
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January 1964 in “Archives of Dermatology” Treatment with vitamin A did not improve the child's skin condition.
1 citations
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April 2018 in “Journal of Investigative Dermatology” Simvastatin helps hair regrowth in autoimmune alopecia by directly affecting T cells.
113 citations
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June 2010 in “Biological Chemistry” Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
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April 2024 in “Health Science Reports” Younger patients with severe alopecia areata often have nail problems.
3 citations
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February 2022 in “Canadian Medical Association Journal” Severe hypothyroidism can cause eyebrow hair loss, but improves with thyroid hormone treatment.
April 2024 in “International Journal of Research Publication and Reviews” Alopecia areata causes hair loss with varied treatment responses and frequent relapses.
26 citations
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March 2006 in “Endocrine, metabolic & immune disorders. Drug targets” This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
April 2018 in “Journal of Investigative Dermatology” People with alopecia areata have higher levels of a heart disease marker in their blood.
24 citations
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May 1985 in “The Journal of Clinical Endocrinology & Metabolism” A circulating inhibitor caused insulin resistance, but clomiphene improved symptoms.
4 citations
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May 2014 in “Javma-journal of The American Veterinary Medical Association” The cat had liver cancer and a related hair loss condition, with a likely cause being bile duct cancer.
4 citations
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November 2015 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Eosinophilic esophagitis may trigger alopecia areata in some patients.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A compromised gut may trigger the autoimmune hair loss condition Alopecia Areata.
2 citations
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December 2001 in “Dermatologic Therapy” Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.
71 citations
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May 1975 in “The American journal of surgery” The patient's liver did not fully grow back and she had serious temporary side effects after a very large liver surgery.
18 citations
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January 1987 in “PubMed” Zinc deficiency in alcoholic cirrhosis patients causes skin issues and other symptoms, which improve with zinc treatment.
2 citations
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May 2021 in “Neuropathology & applied neurobiology/Neuropathology and applied neurobiology” Correct diagnosis and treatment are crucial for effective management of lipid storage myopathies.
July 2022 in “International Journal of Contemporary Medicine” Lower Paraoxonase 1 levels in alopecia areata patients suggest antioxidant treatment might help.
12 citations
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July 1957 in “Journal of Investigative Dermatology” Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.
18 citations
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December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Alopecia areata is a hair loss condition that often starts before age 30 and can affect various body parts, with unpredictable hair regrowth chances.
December 2021 in “Journal of Cosmetic Dermatology” Thiol/disulfide balance is normal in male AGA patients but shifts towards oxidative stress with emotional stress and low vitamin D.
65 citations
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September 2014 in “Orphanet Journal of Rare Diseases” Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.