20 citations
,
January 2017 in “Experimental Dermatology” Igf1r helps regulate hair growth cycles.
March 2023 in “Journal of Student Research” Humans likely became hairless to better regulate body temperature.
April 2017 in “Journal of Investigative Dermatology” Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
33 citations
,
September 1987 in “American Journal of Medical Genetics” Uncombable hair is inherited dominantly with complete penetrance.
2 citations
,
December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.
28 citations
,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
2 citations
,
July 2024 in “Indian Journal of Dermatology” Adults with alopecia areata often have empty follicular openings, while children show more honeycomb pigment patterns.
Hairlessness in mammals is caused by combined changes in genes and regulatory regions.
2 citations
,
October 2010 in “Journal of dermatological treatment” External treatments can change hair growth patterns in nude mice.
31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
September 2023 in “British Journal of Dermatology” Some cases of short anagen hair syndrome are linked to specific genetic variations that are also connected to male pattern baldness.
19 citations
,
October 1985 in “British Journal of Dermatology” The document concludes that unruly hair can be congenital or acquired, often lacks specific treatments, and can be managed with oils and short hairstyles.
30 citations
,
March 1996 in “British Journal of Dermatology”
176 citations
,
April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
August 2012 in “Nature Cell Biology” Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.
November 2023 in “British Journal of Dermatology” Mutations in the WNT10A gene cause Short Anagen Hair syndrome and increase the risk of male pattern hair loss.
7 citations
,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
22 citations
,
February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
66 citations
,
December 1999 in “Journal of Investigative Dermatology” New mutations in the hairless gene may cause hair loss and affect bone development.
August 2018 in “Journal of Investigative Dermatology” Humans evolved to have less hair and more sweat glands than chimpanzees and macaques.
12 citations
,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
23 citations
,
July 1997 in “British Journal of Dermatology” The inner root sheath is vital for hair follicle stability during growth changes.
58 citations
,
April 2009 in “Dermatologic Surgery” Most women have a widow's peak and specific hairline features useful for designing hair restoration surgery.
47 citations
,
July 1997 in “British Journal of Dermatology” The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
2 citations
,
January 2019 in “Dermatology Review” Pigmented vellus and upright regrowing hairs predict hair regrowth in severe alopecia.
April 2017 in “Journal of Investigative Dermatology” A virus protein can activate a pathway that may lead to abnormal hair follicle development.
January 2022 in “Open Access Macedonian Journal of Medical Sciences” A 5-year-old boy with alopecia totalis had temporary hair regrowth with treatment but relapsed, highlighting the need for thorough investigation and holistic care.
August 2016 in “Journal of Investigative Dermatology” Human hair follicles have a scent receptor that can influence hair growth.
6 citations
,
May 2006 in “Skinmed” Androgens contribute to common male hair loss; more research needed for hair growth medication.
April 2017 in “Journal of Investigative Dermatology” Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.