research Moniletrix. Observación de esta infrecuente displasia pilosa en dos hermanos. Reporte clínico y dermatoscópico
Monilethrix is a genetic hair disorder affecting hair shape, seen in two brothers.
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research Sertolioma in a Canadian Husky: Relationship between Tumor, Hormones, Neurons and Skin
Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
research Sutura Tricofítica: Vantagens e Indicações Cirúrgicas
A sutura tricofítica melhora a aparência de cicatrizes em transplantes de cabelo e outras áreas pilosas.
research 862 Defining the molecular signature of the hair follicle dermal sheath and its functional requirement for hair cycle progression during catagen
The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
research 864 Catalytic-dependent and -independent activities of Polycomb repressive complex 1 differentially regulate skin stem cell specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research 860 Understanding cellular & molecular responses in the treatment of pediatric lymphatic anomalies
Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
research 865 Conditional ablation of JAK-STAT5 signaling induces anagen hair growth
Blocking JAK-STAT5 signaling in mice leads to hair growth.
research Finasterida tópica y alopecia androgenética masculina y femenina
Topical finasteride may help treat hair loss in men and women.
research 689 Regional differences in scalp innervation: A pilot study of the healthy scalp
The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
research 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation
BMP signaling controls hair growth and skin color.
research DRUG NEWS
The FDA approved a new breast cancer treatment, found flu shots may reduce heart risks, questioned the safety of fast-tracked drug approvals, showed statins don't help with certain pneumonia, and approved a new dementia imaging agent.
research Contents
The document concludes that new treatments for skin conditions are complex but effective, including spironolactone for female hair loss and propranolol for infantile hemangiomas.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research Insulin Resistance and Polycystic Ovary Syndrome
Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
research Response of Drs. J. E. Pope and E. H. Makela to the Article “Depression Circumstantially Related to the Administration of Finasteride for Androgenetic Alopecia” (J Dermatol, 29, 665-669, 2002): Reply from the Authors of the Questioned Paper
Authors defend finasteride-depression link, suggest detailed medical history, and call for more investigation.
research 863 Molecular basis of hair follicle donor dominance in androgenetic alopecia and sexual dimorphism of the skin
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
research Androgenetic Alopecia in Adolescents
Topical minoxidil helps treat hair loss in teens, but more research needed for safe options.
research Effect of petroleum ether and ethanol fractions of seeds of Abrus precatorius on androgenic alopecia
The seeds of Abrus precatorius, when processed, can prevent hair loss more effectively than common treatments.
research Telogen Effluvium
Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
research Dedifferentiation of committed epithelial cells into stem cells in vivo
Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
research Modulating the stem cell niche for tissue regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research A family business: stem cell progeny join the niche to regulate homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Female pattern hair loss
Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
research Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia
Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
research Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne
Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
research Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.