The naked mutation in mice causes hair loss and helps identify keratin genes.
101 citations
,
August 2003 in “Journal of comparative neurology” Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
1 citations
,
October 1996 in “Dermatologic clinics” Adiponectin reduces inflammation and bone loss in joint replacements.
January 2005 in “Chinese Journal of Veterinary” Hairless mice lose hair by 3-4 weeks, develop thicker, folded skin, and show pigmentation differences.
49 citations
,
January 2006 in “Developmental Dynamics” Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.
April 1974 in “Pediatric Research” The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.
December 2024 in “European journal of medical research” April 2019 in “Journal of Investigative Dermatology” Researchers created a new mouse model for studying scleroderma.
12 citations
,
August 1984 in “Genetics Research” The N gene affects the protein makeup of mouse hair.
25 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” A new mouse model helps understand and find treatments for alopecia areata.
September 2019 in “Journal of Investigative Dermatology” Researchers successfully used nude mice to study human hair growth, which could help with future hair research.
April 2019 in “Journal of Investigative Dermatology” The humanized AA mouse model is better for testing new alopecia areata treatments.
1 citations
,
April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
15 citations
,
October 1976 in “Biochemical Journal” Naked-mouse hair lacks certain proteins and has less soluble fibril.
January 2011 in “Open Collections” Mouse preputial glands are highly developed sebaceous glands that mainly secrete neutral fat droplets.
48 citations
,
July 1988 in “PubMed” Rhino mice show significant meibomian gland changes, making them a potential model for studying gland disorders.
35 citations
,
November 1931 in “Journal of Genetics” Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.
57 citations
,
August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
January 2004 in “Laboratory Animal Science and Administration” The hairless mutant gene causes early hair loss and affects skin and thymus development in mice.
8 citations
,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Mouse models help understand alopecia areata and find treatments.
2 citations
,
October 2010 in “Journal of dermatological treatment” External treatments can change hair growth patterns in nude mice.
January 2005 in “Journal of Zhejiang University(Sciences Edition)” Yuyi hairless mice lose hair after birth, develop thick, loose skin with folds, and show disorganized skin structure as they age.
3 citations
,
January 2004 in “Elsevier eBooks” December 2025 in “Biology” Male and female mice handle stress differently.
March 2022 in “Osaka City University (Osaka City University)” Ovariectomy in mice affects hair growth and skin thickness, suggesting potential for obesity treatment research.
46 citations
,
September 2007 in “Journal of Investigative Dermatology” 17 citations
,
November 1967 in “American Journal of Anatomy” Hairless mice have longer hair follicles and abnormal structures during the catagen phase.
June 2025 in “International Journal of Applied Pharmaceutics” A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
September 2022 in “F1000Research” Removing hair from mice without reproductive glands led to grey hair, possibly helping to understand greying in aging.
7 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil can promote hair growth in hairless mice.