January 2020 in “Columbia Academic Commons (Columbia University)” Certain genetic changes in the STX17 and KRT82 genes contribute to hair loss in alopecia areata.
38 citations
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July 2009 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” Alopecia areata is a common autoimmune disease affecting hair follicles, with unclear causes and a need for better treatments.
23 citations
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November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
8 citations
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January 2015 in “International journal of trichology” A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.
June 2026 in “Wiener klinische Wochenschrift” New treatments for alopecia areata show promise but need ongoing use and have infection risks.
November 2025 in “Figshare” SQSTM1 is linked to increased risk of alopecia areata.
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
New treatments for alopecia areata, like JAK inhibitors and immunomodulators, are promising.
January 2011 in “Repository KITopen (Karlsruhe Institute of Technology)” Blocking certain proteins on immune cells may help treat alopecia areata.
155 citations
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December 2002 in “Journal of Investigative Dermatology” Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
120 citations
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February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
25 citations
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May 2011 in “Dermatologic therapy” New treatments for alopecia areata may target specific immune cells and pathways involved in hair loss.
17 citations
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July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
10 citations
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January 2019 in “International Immunology” Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
2 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The conclusion is that a new method could improve the identification of autoimmune targets in alopecia areata, despite some limitations.
1 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
November 2025 in “Frontiers in Immunology” Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
September 2023 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” The FDA approved Litfulo® for treating severe alopecia areata in people aged 12 and older.
105 citations
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March 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.
7 citations
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January 2012 in “International Journal of Trichology” Two siblings both had a rare case of alopecia areata at the same time.
1 citations
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November 2018 in “immuneACCESS” Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.
March 2025 in “Medical Science of Ukraine (MSU)” Alopecia areata is an autoimmune disease causing hair loss, linked to immune and gut issues, needing more research for better treatments.
May 2024 in “The Journal of Immunology” Alopecia Areata can develop without perforin-mediated cytolysis.
April 2020 in “El-Minia Medical Bulletin” Microneedling is an effective treatment for hair regrowth in Alopecia Areata.
March 2017 in “Medicina y Laboratorio” Alopecia areata symptoms may improve after treating Helicobacter pylori infection.
Alopecia areata is an autoimmune disease that targets hair follicles.
54 citations
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January 2012 in “Vitamins & Trace Elements” People with Alopecia Areata have lower vitamin D levels.
1 citations
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August 2016 in “Journal of Investigative Dermatology” Vδ1+ T-cells in the skin contribute to hair loss in alopecia areata and could be targeted for treatment.
May 2024 in “The Journal of Immunology” IL-27 can prevent hair loss in alopecia areata.
November 2022 in “Journal of Investigative Dermatology” Mitochondrial stress can lead to atopic dermatitis.