503 citations
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May 2009 in “Cell stem cell” Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
79 citations
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November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
33 citations
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January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
7 citations
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November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
5 citations
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July 2013 in “Our Dermatology Online” Lichen planopilaris is the most common type of scarring hair loss observed, with a variety of symptoms and tissue changes.
VDAC2 promotes cell death in cashmere goat hair follicles through the P53 pathway.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
556 citations
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September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
107 citations
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August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
60 citations
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April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
54 citations
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January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
53 citations
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April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
38 citations
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September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
30 citations
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May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
15 citations
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December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
19 citations
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March 2017 in “PLoS ONE” PSU are better than THF at regenerating skin layers in lab models.
2 citations
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September 2014 in “The American Journal of Cosmetic Surgery” Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
Understanding hair follicle signaling can improve hair disorder treatments.
June 2024 in “Skin Appendage Disorders” Both PRP and MZT treatments can significantly improve hair growth in patients with androgenetic alopecia.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
32 citations
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November 2012 in “Aesthetic Surgery Journal” Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.
55 citations
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September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
53 citations
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June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
11 citations
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July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
1 citations
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November 2024 in “Bone Reports” Cellularity can estimate mesenchymal stem cell concentration in bone marrow, aiding regenerative medicine.
March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
December 2025 in “Medical Sciences” Regenerative therapies show promise for hair regrowth, but more research and standardization are needed.
January 2024 in “Updates in clinical dermatology”
December 2020 in “Journal of Aesthetic Nursing” Injecting platelet-rich plasma into the scalp stimulates hair growth, increases hair density, and treats hair loss effectively with minimal side effects.