5 citations
,
October 2021 in “Clinical, cosmetic and investigational dermatology” Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
2 citations
,
April 2025 in “Biologics” Dupilumab and ustekinumab are promising treatments for alopecia areata, showing significant hair regrowth.
March 2026 in “JID Innovations” Aire mutation reduces alopecia areata, while Notch4 mutation prevents it in mice.
March 2026 in “Journal for ImmunoTherapy of Cancer” Long-term data and a team approach are needed to manage chronic side effects from cancer treatments.
December 2024 in “Journal of Clinical Medicine” Minoxidil shows promise for alopecia areata, but more research is needed before it can be recommended as a primary treatment.
December 2024 in “Pharmaceutics” Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
49 citations
,
August 2022 in “Frontiers in Immunology” Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.
4 citations
,
January 2023 in “Skin health and disease” Blocking Janus kinase 1 helps stop inflammation and regrow hair, making it a good treatment for hair loss from alopecia areata.
3 citations
,
September 2021 in “JAAD case reports” Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.
2 citations
,
September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
July 2023 in “International Journal of Trichology” The man's hair turned white suddenly but returned to normal on its own in 6 months.
31 citations
,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
45 citations
,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
24 citations
,
July 2021 in “Pharmaceutics” Ruxolitinib cream effectively targets and treats inflammatory skin diseases.
19 citations
,
December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
4 citations
,
June 2025 in “Cell Reports” Clonally expanded CD8+ T cells cause alopecia areata.
3 citations
,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
2 citations
,
July 2025 in “Frontiers in Veterinary Science” MicroRNAs and AI can improve cashmere goat hair quality and aid in hair disorder diagnosis.
40 citations
,
January 2022 in “Nutrients” Diet can influence inflammatory skin diseases.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
355 citations
,
January 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
277 citations
,
December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
253 citations
,
December 2007 in “Journal of Investigative Dermatology” Hair follicles prevent NK cell attacks to avoid hair loss.
227 citations
,
April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
139 citations
,
October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
102 citations
,
January 2022 in “Mayo Clinic Proceedings” COVID-19 can cause long-term health issues in many body systems, and vaccination is important to prevent these effects.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
88 citations
,
August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
77 citations
,
June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.