38 citations
,
September 1997 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in mice causes hair loss and skin issues due to a defect in a gene affecting cell adhesion.
September 2023 in “Journal of the American Academy of Dermatology”
43 citations
,
May 2011 in “Dermatologic Therapy” Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
42 citations
,
September 1985 in “British Journal of Dermatology” Trichothiodystrophy causes abnormal protein deposits and distortion in hair follicles.
9 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
April 2023 in “Journal of Investigative Dermatology” Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
6 citations
,
March 2016 in “PLoS ONE” The patient's hair was thinner and had fewer lipids due to a genetic mutation.
4 citations
,
November 1999 in “PubMed” Monilethrix is a rare hair disorder causing beaded, fragile hair, often improving on its own over time.
April 2018 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” All types of alopecia involve hair follicle damage, especially in alopecia areata.
32 citations
,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
52 citations
,
May 2009 in “Human & experimental toxicology” Hair loss and polyneuropathy improved, but severe vision impairment persisted.
September 2013 in “Science” Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.
54 citations
,
December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
Smad4 is crucial for muscle repair, especially in aging, by promoting cell growth over differentiation.
4 citations
,
December 2020 in “Journal of Dermatology” Impaired autophagy may cause hair loss by triggering early catagen.
6 citations
,
May 2014 in “Biomarkers and Genomic Medicine” Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.
April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
20 citations
,
April 2000 in “Experimental dermatology” ODC transgenic mice can model human hair loss with skin lesions.
72 citations
,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
July 2025 in “Journal of Investigative Dermatology” Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.
January 2015 in “Indian Dermatology Online Journal” The patient's hair loss is most likely due to diffuse alopecia areata.
April 2016 in “Actas Dermo-Sifiliográficas” The document concludes that a unique target-like hair regrowth pattern in alopecia areata may be more common than thought and should be properly identified.
64 citations
,
May 1981 in “Clinical and Experimental Dermatology” A possible link exists between hair follicle abnormalities, hair loss, and muscle weakness.
April 2020 in “International journal of research in dermatology” An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.
16 citations
,
July 2021 in “American Journal of Medical Genetics Part A” Mutations in the LSS gene cause hair loss and may affect brain development, with varying severity.
January 2025 in “International Journal of Pharma Medicine and Biological Sciences” DP cells interact with immune cells, possibly causing hair loss in Alopecia Areata.
19 citations
,
June 2002 in “American Journal of Dermatopathology” Apoptosis contributes to hair loss in androgenetic alopecia.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.