January 2025 in “The International Journal of Gastroenterology and Hepatology Diseases” Vitamin B12 is crucial for hair and nerve health, and its malabsorption can cause hair loss and nerve damage.
March 2018 in “Gazi medical journal” Adults with Beta Thalassemia Major are more likely to have skin, hair, and nail disorders.
October 2025 in “The American Journal of Gastroenterology” Excessive zinc intake can cause liver failure.
Severe hypothyroidism can cause temporary liver and kidney issues, which improve with thyroxine treatment.
April 2022 in “SDÜ Tıp Fakültesi Dergisi” Sodium benzoate at higher doses can harm kidney and liver functions and cause oxidative stress and DNA damage.
26 citations
,
June 2005 in “Journal of The American Academy of Dermatology” Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
73 citations
,
October 2001 in “Epilepsia” Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
3 citations
,
October 1976 in “BMJ” Sodium valproate can cause low platelets and hair loss.
62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
5 citations
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January 2023 in “IDCases” Albendazole and praziquantel can cause severe side effects, especially with prolonged use or liver issues.
28 citations
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March 1986 in “The American journal of medicine” Too much vitamin A can cause liver damage and skin issues.
November 2025 in “Mendeley Data” JAK inhibitors can be safely used for alopecia areata in patients with latent hepatitis B or stable tuberculosis with proper monitoring.
30 citations
,
January 2007 Cyclophosphamide can cause serious short-term and long-term side effects, including increased cancer risk and infertility.
January 2011 in “Arqueología, historia y viajes sobre el mundo medieval/Arqueología, historia y viajes sobre el mundo medieval” Sodium valproate can cause severe liver disease and side effects, sometimes leading to death.
12 citations
,
February 1986 in “PubMed” Injecting newborn mice with a niacin blocker caused skin, gut, and brain damage similar to human pellagra.
January 1981 in “The Journal of Toxicological Sciences” Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
31 citations
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December 1997 in “Developmental Medicine & Child Neurology” Biotinidase deficiency can cause vision and walking problems in children and can improve with biotin treatment.
January 2014 in “대한피부과학회지” A hepatitis B patient lost hair in patches after starting and stopping a treatment with pegylated interferon alpha2a.
August 2013 in “Hospital Pharmacy” Certain medications can cause serious side effects, including skin reactions, stroke, muscle disorders, tongue swelling, hair loss in women, and liver failure.
10 citations
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January 1992 in “Screening” Newborn screening for biotinidase deficiency is effective in preventing severe complications.
September 1989 in “Neuroscience letters” People need different amounts of biotin based on age, and not getting enough can cause health problems.
August 2025 in “Quality in Sport” Vitamin A is essential but too much can be harmful, especially from supplements.
65 citations
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August 2016 in “Metabolic brain disease” Children with autism have lower levels of essential and toxic trace elements in their hair.
September 2023 in “Translational medicine reports” Minoxidil ingestion can raise liver enzyme levels.
January 2016 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” CAP7.1 is generally safe at 200 mg/m²/day, but can cause fatigue, nausea, hair loss, fever, and blood-related issues.
3 citations
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March 2017 in “Regulatory toxicology and pharmacology” Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
37 citations
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October 2004 in “Adolescent Medicine Clinics” Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
23 citations
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May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.