research Histochemical observations of lectin-binding sites and keratin distribution in calcifying epithelioma of Malherbe.
Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.
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research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration
The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
research In brief
Pilomatricomas don't follow the usual hair follicle cell differentiation process.
research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures
The method increases stem-like cells for better skin regeneration.
research Expression of the hair stem cell-specific keratin 15 in pilar tumors of the skin.
K15 staining helps distinguish basal cell carcinoma from trichoepithelioma.
research A pure, monolayer culture of Merkel cells from sinus hair follicles of the rat
Adding fetal calf serum to the medium kept Merkel cells alive and changed their shape.
research Transport of Biotin in Human Keratinocytes
Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
research 1347 Updated skin transcriptomic atlas depicted by reciprocal contribution of single-nucleus RNA sequencing and single-cell RNA sequencing
The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
research Generating iPSCs with a High-Efficient, Non-Invasive Method—An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming
The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Study on the distribution of hair keratin in normal hair follicles by immunohistochemical staining
Different keratins in hair follicles can help identify hair tumor origins.
research Collagen-type synthesis in human-hair papilla cells in culture
research 132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function
Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
research Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.
research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage
Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis
Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.
research Mechanical and biological properties of keratose biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
research Sequences and differential expression of three novel human type-II hair keratins
Hair differentiation starts earlier than thought, involving multiple type-II keratins.
research Analysis on the maintenance mechanisms of human interfollicular epidermal stem cell and their niche
Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Characterization of LHTric-1, a new monospecific monoclonal antibody to the trichocyte keratin Ha1
LHTric-1 is a specific antibody useful for studying hair and nail formation.
research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
PDCD4 is important for controlling skin cell growth and healing.
research Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions
Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research Characterization of Epithelial Hair Follicle Stem Cells in Lichen Planopilaris and Folliculitis Decalvans Through Keratin 19 Expression
Keratin 19 may help diagnose and treat certain types of permanent hair loss.
research The Catalog of Human Hair Keratins
Human hair keratins were cataloged, showing their roles in hair differentiation stages.
research Regulation of Keratin Gene Expression in Hair Follicle Differentiationa
Keratin gene regulation is similar across mammals, affecting hair follicle differentiation.
research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.