359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
309 citations
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May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
304 citations
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July 2006 in “Journal of The American Academy of Dermatology” Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.
242 citations
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February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
236 citations
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July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
234 citations
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December 1996 in “Journal of The American Academy of Dermatology” Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
222 citations
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October 1993 in “Journal of The American Academy of Dermatology” Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.
209 citations
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March 1989 in “Journal of The American Academy of Dermatology” Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
192 citations
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June 1992 in “Journal of The American Academy of Dermatology” Hair loss can cause low self-esteem, anxiety, and depression in men.
187 citations
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June 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats frontal hair loss with few side effects.
165 citations
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December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
162 citations
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August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
157 citations
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April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
152 citations
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April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
151 citations
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February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
151 citations
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August 2010 in “British Journal of Dermatology” Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.
139 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Androgenetic alopecia in women needs more research and better management strategies.
139 citations
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July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
138 citations
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
135 citations
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August 1994 in “Clinical Endocrinology” Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.
133 citations
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February 2017 in “PLoS Genetics” Genetic factors can help predict male pattern baldness risk.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
125 citations
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May 2007 in “Journal of The American Academy of Dermatology” The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.
122 citations
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April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
121 citations
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March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
120 citations
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
119 citations
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October 1992 in “Fundamental & Clinical Pharmacology” Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
115 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.
112 citations
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October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.