759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
April 2017 in “Journal of Investigative Dermatology” Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
January 2015 in “Springer eBooks” Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
17 citations
,
January 2010 in “PubMed” Optimal storage solutions and effective additives are crucial for improving the survival of hair transplant grafts.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
19 citations
,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
68 citations
,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
22 citations
,
August 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
90 citations
,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
58 citations
,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
55 citations
,
July 2016 in “Dermatologic Therapy” Multiple treatments work best for hair loss.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
27 citations
,
July 1990 in “International Journal of Dermatology” A pulsed electrical field safely and effectively increased hair growth.
19 citations
,
March 2003 in “Journal of Investigative Dermatology” Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
15 citations
,
April 2001 in “Journal of Dermatological Science” KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
12 citations
,
February 1999 in “British Journal of Dermatology” Minoxidil increased small openings in blood vessel walls near growing hair in rats.
October 2025 in “Journal of Translational Medicine” Combining biomaterials and cell pathways can improve hair follicle regeneration.
November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
June 2022 in “International journal of drug delivery technology” Nebivolol cream may be a promising hair loss treatment by improving blood flow and nourishing hair follicles.
Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
December 2022 in “Research Square (Research Square)” Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
October 2022 in “Research Square (Research Square)” Key genes linked to immune response are highly active in lupus-affected hair follicles.
8 citations
,
November 2017 in “Journal of Investigative Dermatology” AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
6 citations
,
January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
72 citations
,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
9 citations
,
July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.