research Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia
Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
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research Infertility Treatment in Polycystic Ovary Syndrome: Lifestyle Interventions, Medications and Surgery
Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor
Curcumin, EGCG, barringtozenol, and finasteride are effective VEGFR inhibitors.
research The triple rotation scalp flap revisited: a case of reconstruction of cicatricial pressure alopecia
The triple rotation scalp flap technique successfully reconstructed a man's scalp with natural-looking hair growth and minimal scarring.
research Janus kinase inhibition for the treatment of refractory frontal fibrosing alopecia: A case series and review of the literature
JAK inhibitors, like ruxolitinib, may effectively treat frontal fibrosing alopecia.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research Efficacy of JAK 1/2 inhibition in the treatment of diffuse non-scarring alopecia due to systemic lupus erythematosus
Baricitinib might help treat hair loss in lupus patients, but more research is needed.
research Metabolic, Behavioral, and Reproductive Effects of Vertical Sleeve Gastrectomy in an Obese Rat Model of Polycystic Ovary Syndrome
Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
research Sudden Akathisia After a Ziprasidone Dose Reduction
Lowering the dose of ziprasidone can cause sudden restlessness and urge to move in patients.
research DERMATOLOGIC SIDE EFFECTS OF PSYCHOPHARMACOLOGIC AGENTS
Some psychiatric drugs can cause skin problems, but serious reactions are rare.
research Male skin and ingredients relevant to male skin care
Using specific cleansers and moisturizers with niacinamide improves men's skin hydration and health.
research Severe and Fatal Phenobarbitone Eruptions
Phenobarbitone can cause severe and sometimes fatal skin reactions.
research Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors
New oral treatments for adult hair loss show promise, especially JAK inhibitors, with mild side effects.
research Predictors and Management of Inadequate Response to JAK Inhibitors in Alopecia Areata
Switching JAK inhibitors or using dupilumab may help some alopecia areata patients who don't respond well to initial treatments.
research Polycystic ovary syndrome: a common reproductive syndrome with long-term metabolic consequences
Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
research Inherited Disorders of Corneocyte Proteins
Ichthyoses are genetic skin disorders that affect the skin's barrier function.
research Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-analysis
Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
research Hair removal and bioavailability of chemicals: Effect of physicochemical properties of drugs and surfactants on skin permeation ex vivo
Hair removal methods damage the skin barrier and affect substance penetration.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Choice of treatment for women with polycystic ovary syndrome
The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.
research From Piezoelectric Nanogenerator to Non-Invasive Medical Sensor: A Review
Piezoelectric Nanogenerators are promising for non-invasive health monitoring but need efficiency and durability improvements.
research Alopecia universalis unresponsive to treatment with tofacinitib: report of a case with a brief review of the literature
Tofacitinib helped psoriasis but not alopecia universalis, needing more research.
research INFLUENCE OF CLIPPING AND CHEMICAL EPILATION ON HAIR GROWTH IN MICE1
Certain treatments can speed up local hair growth in mice but don't change the overall hair growth pattern.
research Janus kinase inhibitors for alopecia areata
JAK inhibitors offer new hope for treating severe alopecia areata.
research Efficacy and safety of different JAK inhibitors in the treatment of alopecia areata: a network meta-analysis
Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.
research Emerging drugs for the treatment of alopecia areata
New drugs for alopecia areata show promise but aren't universally effective, and hair loss often returns after stopping treatment.
research Understanding the Characteristics of the Scalp for Developing Scalp Care Products
Improving the scalp's barrier function can help reduce dandruff and maintain scalp health.
research Shedding light on therapeutics in alopecia and their relevance to COVID-19
Some alopecia treatments might help treat COVID-19, but more research is needed.