292 citations
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April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
186 citations
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February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
175 citations
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January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
143 citations
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January 2007 in “The American Journal of Human Genetics” Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
131 citations
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September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
131 citations
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November 2010 in “Journal of the American Academy of Dermatology” Cyclosporine is effective for skin conditions but has declined in use due to toxicity concerns.
129 citations
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October 2017 in “BMC Genomics” The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.
71 citations
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February 2012 in “The American Journal of Human Genetics” A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
70 citations
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August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.
68 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
66 citations
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August 2007 in “Applied and environmental microbiology” The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
63 citations
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January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
60 citations
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September 2023 in “Science” BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.
59 citations
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August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
56 citations
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March 2017 in “Plant and Cell Physiology” Light sheet fluorescence microscopy effectively measures calcium changes in Arabidopsis root hairs.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
48 citations
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September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
45 citations
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November 2024 in “International Journal of Molecular Sciences” Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
44 citations
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September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
42 citations
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August 2022 in “Diagnostics” Diagnose PCOS in teens using irregular periods and high androgen levels, not ultrasound.
41 citations
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July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
41 citations
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March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
38 citations
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April 2020 in “IntechOpen eBooks” Phenylalanine may help with depression but can cause issues if not properly processed.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
37 citations
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April 2018 in “Journal of Allergy and Clinical Immunology” A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.
37 citations
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October 2015 in “PeerJ” Perming significantly changes hair's molecular structure, while shampoo and conditioner do not.
35 citations
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January 2024 in “BioMolecular Concepts” Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.
34 citations
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December 2021 in “Journal of Clinical Medicine” Men with BPH should discuss potential sexual side effects with doctors before treatment, as some treatments can affect ejaculation.
28 citations
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September 2020 in “International Journal of Molecular Sciences” Leucocyte-rich platelet-rich plasma boosts cell activity and helps wound healing.