research Epigenetic regulations on skin wound healing: implications from current researches.
Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
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research Morphological characteristics and notes of the skin in preclinical toxicity assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration
Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets
Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.
research General Dermatology
The document explains various skin conditions and their treatments.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
research Biocompatible nanoparticles and vesicular systems in transdermal drug delivery for various skin diseases
Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Exosomes as a novel pathway for regulating development and diseases of the skin (Review)
Exosomes are important for skin health and could help diagnose and treat skin diseases.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Defining the transcriptional signature of esophageal-to-skin lineage conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology
Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
research IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice
Blocking IL-17a can improve age-related smell loss in mice.
research TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells
TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
research The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research 1334 Beyond goosebumps: Interactions between the hair follicle, the arrector pili muscle, and the sympathetic nerve during development and hair follicle regeneration
Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Effects of Visible Light on the Skin†
Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.