15 citations
,
October 2014 in “Journal of Investigative Dermatology” New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.
April 2018 in “Journal of Investigative Dermatology” Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
20 citations
,
January 2014 in “Journal of skin cancer” Most people with basal cell carcinoma on their head or neck were 60-70 years old, and it often came back even after being fully removed, especially in certain areas and types.
10 citations
,
May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
5 citations
,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
May 2015 in “Actas Dermo-Sifiliográficas” A young man was unexpectedly diagnosed with basal cell carcinoma after a scalp examination and confocal microscopy.
63 citations
,
May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
12 citations
,
March 2018 in “Medicine” A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
8 citations
,
May 2019 in “Journal of dermatological treatment” Vismodegib is effective for basal cell carcinoma but has severe side effects.
7 citations
,
October 2019 in “Case reports in endocrinology” A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
The treatment was ineffective in humans.
April 2023 in “Clinical theriogenology” The dog's skin condition improved after removing a tumor that was causing hormone imbalances.
3 citations
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September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.
December 2017 in “British Journal of Dermatology” Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.
April 2016 in “Journal of Investigative Dermatology” Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.
5 citations
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October 2014 in “Gynecological Endocrinology” Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
September 2024 in “Electronic Journal of General Medicine” Diagnosing Sertoli-Leydig cell tumors is challenging due to their unusual symptoms and can occur at any age.
January 2026 in “Immune Network” Regulatory T cells adapt to different environments to control inflammation and support tissue repair.
72 citations
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November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
September 2025 in “Experimental & Molecular Medicine” Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
16 citations
,
March 2015 in “Clinical Cancer Research” The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
Vismodegib effectively treats advanced basal cell carcinoma but requires careful management of serious side effects.
5 citations
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February 2015 in “Journal of Comparative Pathology” High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.
January 2019 in “Publisher” Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.
1 citations
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February 2017 in “Clinical Dermatology Open Access Journal” A rare benign tumor was found in a man's scrotum, highlighting the need for accurate diagnosis.
61 citations
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August 1993 in “PubMed” Basal cell epithelioma likely starts from the hair follicle's outer root sheath.