14 citations
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March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
19 citations
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April 2015 in “Stem Cells” Pro-IGF-II improves muscle repair in old mice.
50 citations
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September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
November 2024 in “The Journal of Cell Biology” Basement membrane changes are crucial for hair follicle development.
September 2013 in “Science” Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.
4 citations
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January 2021 in “Journal of Clinical Medical Research” c-Kit is important for heart regeneration and cancer development.
85 citations
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May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
1 citations
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January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
3 citations
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May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
19 citations
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September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
80 citations
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May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
24 citations
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November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
23 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
1039 citations
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
211 citations
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November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
168 citations
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August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
396 citations
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May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
May 2018 in “Cell stem cell” Myoepithelial cells can repair airways after severe injury.
January 2020 in “Journal of Entomology and Zoology Studies” Canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle.
2 citations
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September 2022 in “Organoid” A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
66 citations
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December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
63 citations
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April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.