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Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.

Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.

Basal stem cells in the skin have distinct types that are crucial for skin structure and health.

Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.

Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

Key genes linked to hair growth and cancer were identified in hairless mice.

GLI and EGF signalling affect Basal Cell Carcinoma development and could be therapeutic targets.

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

GLI2 increases follistatin production in human skin cells.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

MOF controls skin development by regulating genes for mitochondria and cilia.

GLI2 activates GLI1, promoting skin tumor growth and hair development.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

A specific DNA region controls skin cell gene expression by working with certain proteins.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Middle-aged skin shows aging signs, and quercetin might help delay them.

CD4+ skin cells may be precursors to basal cell carcinoma.

The research shows that skin cancer likely originates from hair follicles and that certain cell populations expand to promote skin cancer growth.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

Ovol2 is essential for normal skin and hair regeneration.

The study identifies four distinct zones in the fetal vaginal epithelium, enhancing understanding for potential applications in women's health.

Researchers identified new cell types and genes in early hair follicle development.

Keratin 15 helps keep skin cells in a young, undifferentiated state.

YAP and TAZ are crucial for skin cell growth and repair.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.