158 citations
,
July 1993 in “The Journal of Pediatrics” Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.
145 citations
,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
142 citations
,
August 2007 in “Journal of The American Academy of Dermatology” New 5% minoxidil foam effectively promotes hair growth and is safe for use.
136 citations
,
April 2016 in “Dermatologic Surgery” PRP treatment helps hair growth and density in androgenetic alopecia patients.
130 citations
,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
129 citations
,
October 2000 in “British Journal of Dermatology” Finasteride helps increase hair growth in men with hair loss.
127 citations
,
May 2004 in “PubMed” Finasteride may help some male chronic pelvic pain patients, but more research needed.
123 citations
,
September 1987 in “JAMA” IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
120 citations
,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
116 citations
,
February 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors help with skin conditions but need more research on dosing and safety.
113 citations
,
July 2015 in “Journal of Cosmetic Dermatology” Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.
112 citations
,
May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
107 citations
,
August 2014 in “Dermatologic Surgery” PRP injections improve hair thickness for baldness.
101 citations
,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
101 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
100 citations
,
June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
94 citations
,
September 2008 in “Journal of the American Academy of Dermatology” Traction alopecia is more common in African women than girls, especially when traction is applied to chemically relaxed hair; avoiding such hairstyles may reduce the risk.
91 citations
,
December 2017 in “Systems Biology in Reproductive Medicine” Lower SHBG levels may increase the risk of PCOS.
91 citations
,
December 2010 in “Stem Cells” Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
90 citations
,
March 2017 in “JAMA Internal Medicine” Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.
79 citations
,
October 2015 in “Journal of Dermatological Treatment” Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.
78 citations
,
March 2017 in “JAMA Dermatology” Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.
71 citations
,
January 2004 in “Dermatology” Oral finasteride works better than topical minoxidil for hair growth, both are safe.
69 citations
,
December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
68 citations
,
November 2015 in “The Journal of Allergy and Clinical Immunology” Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.
67 citations
,
March 2021 in “Dermatology and Therapy” Alopecia areata greatly harms quality of life, causing emotional and social issues.
67 citations
,
April 2018 in “JAMA Dermatology” Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.
67 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.
66 citations
,
June 2013 in “Journal of Dermatological Treatment” Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.