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PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis

26 citations , August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

research Immunohistochemical demonstration of breast‐derived and/or carcinoma‐associated glycoproteins in normal skin appendages and their tumors

71 citations , February 1992 in “Journal of Cutaneous Pathology”

Antibodies help identify glycoproteins in normal skin and tumor cells.

research Central centrifugal cicatricial alopecia

11 citations , January 2013 in “Indian Dermatology Online Journal”

CCCA is a common, progressive hair loss condition that may not always be linked to hair care practices and requires a biopsy for diagnosis.

research RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling

21 citations , February 2017 in “PLoS ONE”

RhoA helps skin stem cells grow, aiding wound healing.

research Prevalence of CYP21 mutations and IRS1 variant among women with polycystic ovary syndrome and adrenal androgen excess

40 citations , February 2005 in “Fertility and Sterility”

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

20 citations , October 2017 in “Stem Cell Reports”

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

Human-Derived Immortalized Dermal Papilla Cells With Constant Expression of Androgen Receptor

research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

8 citations , March 2020 in “Frontiers in Cell and Developmental Biology”

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

research Study on the Activity of Sheep High-sulfur Keratin Promoter

January 2009 in “China Animal Husbandry & Veterinary Medicine”

The B2C promoter works in sheep cells but not in mouse embryos.

research Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity

11 citations , June 2017 in “Journal of cell science”

AGD1's PH domain is essential for its role in root hair growth and polarity.

research Role of alkaline ceramidase 1 (Acer1) in regulating epidermal homeostasis and tumorigenesis

August 2017 in “Academic Commons (Stony Brook University)”

Acer1 is essential for skin health and affects hair growth and skin cancer risk.

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