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research Androgens’ Effects across the Lifespan in Men and Animal Models

April 2021 in “IntechOpen eBooks”

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

research Decision letter: Effects of lifelong testosterone exposure on health and disease using Mendelian randomization

July 2020

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Interactions Between Lower Urinary Tract Symptoms and Cardiovascular Risk Factors Determine Distinct Patterns of Erectile Dysfunction: A Latent Class Analysis

research Interactions between Lower Urinary Tract Symptoms and Cardiovascular Risk Factors Determine Distinct Patterns of Erectile Dysfunction: A Latent Class Analysis

12 citations , December 2013 in “The Journal of Urology”

Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.

research 12 Treatment of hirsutism with 5α-reductase inhibitors

28 citations , May 1986 in “Clinics in endocrinology and metabolism”

New compounds may soon be tested to treat excessive hair growth in women.

research Post-finasteride syndrome: An emerging clinical problem

26 citations , December 2019 in “Neurobiology of Stress”

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

research Finasteride-Induced Gynecomastia in a 62-Year-Old Man

15 citations , June 1995 in “The American Journal of the Medical Sciences”

Finasteride caused enlarged breast tissue in a 62-year-old man.

Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity

research Development and evaluation of antisense shRNA-encoding plasmid loaded solid lipid nanoparticles against 5-α reductase activity

12 citations , January 2018 in “Journal of Drug Delivery Science and Technology”

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

research Androgen Receptor in Human Health: A Potential Therapeutic Target

12 citations , December 2012 in “Current Drug Targets”

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations , December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

Novel Synthesis of Nicotinamide Derivatives with Cytotoxic Properties

research Novel synthesis of nicotinamide derivatives of cytotoxic properties

51 citations , March 2006 in “Bioorganic & Medicinal Chemistry”

Newly made nicotinamide compounds could potentially treat cancer.

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