research The Effect of 5 -Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
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research Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation
5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
research Anti-androgenic activities of Ganoderma lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Maximum Efficacy of Finasteride Is Obtained within 6 Months and Maintained over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Oral ivermectin in the treatment of scabies
Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.
research Finasteride-associated cataract and intraoperative floppy-iris syndrome
Finasteride may cause cataracts and floppy-iris syndrome.
research The placebo effect and randomized trials: analysis of conventional medicine
The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
research Assessing finasteride-associated sexual dysfunction using the FAERS database
Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
research Economic analysis of finasteride: A model-based approach using data from the Proscar long-term efficacy and safety study
Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Facial Hidradenitis Suppurativa in a 28-Year-Old Male Responding to Finasteride
Finasteride helped treat a 28-year-old's facial skin condition.
research Finasteride and Male Breast Cancer: Does the MHRA Report Show a Link?
No definitive link between finasteride and male breast cancer, but further research is needed.
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Post-finasteride syndrome – does it really exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research Finasteride and the Uncertainties of Establishing Harms
Finasteride's potential harms are hard to accurately measure.
research Inappropriate Sexual Behaviors in Patients with Vascular Dementia: Possible Response to Finasteride
Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
research Aphalangia possibly linked to unintended use of finasteride during early pregnancy
Finasteride use during early pregnancy may cause limb deformities in babies.
research Non-surgical management of BPH: An updated review of current literature and state of the art on natural compounds and medical therapy
Personalized treatment is crucial for effectively managing benign prostatic hyperplasia (BPH).
research Saw palmetto and finasteride in the treatment of category-iii prostatitis/chronic pelvic pain syndrome
Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.
research Targeting a fibrotic bottleneck may provide an opening in the treatment of LUTS
New treatments targeting fibrosis could improve urinary symptoms in BPH.
research The Impact of the 5α-Reductase Inhibitors (5α-RIs) on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin- induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress
Krill oil may help reduce prostate enlargement and growth.
research Study on the mechanism that SNPs related to sex hormone metabolism regulate the imbalance of sex hormones and lead to BPH in rats
Combined finasteride and anastrozole therapy effectively treats BPH, influenced by hormone imbalances and genetics.
research Impact of Finasteride on Serum PSA Levels in Men With BPH: A Systematic Review
Finasteride lowers PSA levels and prostate size, requiring adjusted PSA interpretation for accurate cancer screening.
research African Journal of Biomedical Research
Olive leaves extract may help treat benign prostatic hyperplasia (BPH).
research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research Effect of 5α-reductase inhibitors on sexual function: New contributions
5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.