research A phase 2a study investigating the effects of ritlecitinib on brainstem auditory evoked potentials and intraepidermal nerve fiber histology in adults with alopecia areata
Ritlecitinib is safe and may effectively treat alopecia areata.
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research 709 Nitric oxide-releasing topical therapeutic agent for atopic dermatitis
SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.
research Synthesis of avicequinone c and analogs toward the study of 5α-reductase inhibitory activity
2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.
research High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY 191704, a human type 1 5α-reductase inhibitor, in plasma
Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION
The research found that androgens help control blood flow in the rat prostate through a specific binding site.
research Preparation, Characterization and Molecular Docking Study of some New Pyrazole Derivatives Derived from 2-Mercaptobenzothiazole.
New pyrazole derivatives may help treat hair loss, but more testing is needed.
research The Membrane-Anchored BOTRYTIS-INDUCED KINASE1 Plays Distinct Roles in Arabidopsis Resistance to Necrotrophic and Biotrophic Pathogens
BIK1 gene helps plants resist some pathogens but makes them more vulnerable to others.
research Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture
Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
research Arecaceae
Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
research Auxin and Root Hair Defective Six‐Like 4 Regulate Azospirillum brasilense‐Induced Root Hair Development in Arabidopsis
Azospirillum brasilense promotes root hair growth in Arabidopsis by increasing auxin and activating specific genes.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Synthesis of 4-amidinoimidazoles incorporating a cyanamide moiety : novel precursors for biologically important purines
research Role of Para-Aminobenzoic Acid in Vitamin B-Complex Studies with Mice.
PABA helps prevent gray hair and hair loss in mice.
research Studies on lysosomes—XIII
Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.
research ALLETHRIN INDUCED TOXICOPATHOLOGICAL ALTERATIONS IN ADULT MALE ALBINO RATS
Allethrin caused harmful effects and organ damage in rats, worsening with higher doses and longer exposure.
research Black phosphorus nanosheets encapsulated microneedle for multifunctional therapy for androgenic alopecia
A new treatment using microneedles with black phosphorus and laser helps regrow hair effectively and safely.
research Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase
Some dibenzo compounds might help treat cancer with fewer side effects.
research A comparative study on therapeutic efficacy between topical dinitrochlorobenzene and topical betamethasone in alopecia areata
DNCB is more effective than betamethasone for hair regrowth but has more side effects.
research The effect of Biotin and Bepanthene on hair loss in patients with androgenetic alopecia
research CLORURO DE BENZALCONIO EN EL TRATAMIENTO DE LA DERMATOMICOSIS CAUSADA POR Trichophyton sp. EN EL CUY (Cavia cobayo)
Benzalkonium chloride effectively treats skin fungus in guinea pigs.
research Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
research Administration of Caesalpinia bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
research In silico investigation of possible multi-target drugs against Glutamate S-transferase and prolyl tRNA synthetase in Onchocerca volvulus
Bedaquiline, Telmisartan, Diosmin, Azelastine, and Adapalene may be effective treatments for onchocerciasis.
research The Bis(1,2,3,4-tetrahydroisoquinoline) Alkaloids Cepharanthine and Berbamine Are Ligands of SK Channels
Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.
research Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model
Croton membranaceus root extract can change how drugs are processed in the body.
research Baricitinib Provides Higher Efficacy in Adolescents Relative to Adults With Alopecia Areata Despite More Severe Disease at Baseline: 36-Week Outcomes From BRAVE-AA Trials
Baricitinib works better in adolescents than adults for treating severe alopecia areata.
research Protein-phosphatase inhibitors block root hair growth and alter cortical cell shape of Arabidopsis roots
research 0955 Selective BET inhibition as potential hidradenitis suppurativa treatment
research Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.