research Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro
Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
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research No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene
Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
research New advances in the treatment of thin endometrium
New treatments aim to improve thin endometrium to help more couples with infertility.
research What may be the markers of the male equivalent of polycystic ovary syndrome?
Some men with early hair loss may have a condition similar to PCOS in women.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Hormonal changes in menopause: do they contribute to a ‘midlife hair crisis’ in women?
Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.
research Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia
DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
research Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Interventions for female pattern hair loss
Minoxidil effectively treats female pattern hair loss.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Alopecia and the metabolic syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research Guidelines for management of androgenetic alopecia based on BASP classification-the Asian consensus committee guideline
Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research Polycystic ovarian syndrome
PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Testosterone and the Brain: From Cognition to Autism
Testosterone affects brain functions and contributes to sex differences, influencing conditions like autism.
research A missing piece: the spiny mouse and the puzzle of menstruating species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Female pattern hair loss
FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Interventions for female pattern hair loss
Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
research Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride
Dutasteride does not impair mental function in elderly men with enlarged prostate.