research The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides: A Review
Monosaccharide composition in plant polysaccharides significantly affects their biological activities and therapeutic potential.
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570-600 / 1000+ resultsresearch The effect of St John’s wort on the pharmacokinetics and metabolism of finasteride in man
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
research Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities
Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
research Phytochemical and infra-radiation test of Mangkokan leaf (Nothophanax scutellarum merr.)
Mangkokan leaf contains various beneficial compounds like alkaloids, flavonoids, and steroids.
research Alopecia Associated with Fluconazole Therapy
High doses of fluconazole can cause reversible hair loss.
research Bicalutamide: A review
Bicalutamide may help treat female pattern hair loss.
research Hair growth-promoting activity of components derived from sweet potato shochu.
research Finasteride 98319‐26‐7
research Procyanidin B-2 and the hair-growing activity of proanthocyanidins
Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
research Treatme nt of vitamin-D and calcium to children with hair defluvium
Vitamin-D and calcium effectively treat hair loss in children.
research Vitamin B Prevents Hair from Graying: In Rats
Vitamin B can prevent hair from turning gray in rats.
research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size
Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
research Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research Effects of Transcutol P and Precirol ATO-5 on Percutaneous Absorption of Flutamide from Emulgels
Flutamide emulgel with 1% Transcutol P absorbs better through the skin than other mixtures.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Anti-inflammatory Effects in LPS-treated RAW 264.7 Cells and the Influences on Drug Metabolizing Enzyme Activities by the Traditional Herbal Formulas, Yongdamsagan-Tang and Paljung-san
The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.
research Table 3_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other molecules may help treat hair loss by inhibiting 5-alpha reductase.
research A pilot study of 2% tofacitinib cream with narrowband ultraviolet B for the treatment of facial vitiligo
Using 2% tofacitinib cream with narrowband ultraviolet B improved facial vitiligo by 70% in patients who didn't respond to previous treatments, with no side effects reported.
research Bioactivity guided isolation and characterization of the phytoconstituents from the Tridax procumbens
Tridax procumbens plant parts boost immune response in mice.
research Review: Dutasteride, fesoterodine, and finasteride are beneficial for lower urinary tract symptoms in older patients
Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.
research RAPID ALKALINIZATION FACTOR 22 is a key modulator of the root hair growth responses to fungal ethylene emissions in Arabidopsis
RALF22 is essential for root hair growth in response to fungal emissions in Arabidopsis.
research Investigating bioactive phytochemicals in bulb and shoot of Allium longisepalum Bertol. from Iran
The bulb and shoot of Allium longisepalum contain various compounds with potential health benefits, including antioxidant and anti-inflammatory properties.
research Natural products reverse cancer multidrug resistance
Natural products can help overcome cancer drug resistance.
research Multi-omics revealed that the postbiotic of hawthorn-probiotic alleviated constipation caused by loperamide in elderly mice
Hawthorn-probiotic postbiotic may relieve constipation in elderly.
research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis
Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.
research Sensory and Nutrition Evaluation of Soups Supplemented with Fresh Hibiscus rosa sinensis Flowers
Soups with 5% or 10% hibiscus are tasty and nutritious.
research Investigation of intermolecular interactions in finasteride drug crystals in view of X-ray and Hirshfeld surface analysis
Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.