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Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Visceral and Subcutaneous Adipose Tissues of Patients with Polycystic Ovary Syndrome Is Associated with Adiposity

research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity

18 citations , December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology”

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

research The polycystic ovary syndrome: a position statement from the European Society of Endocrinology

467 citations , October 2014 in “European Journal of Endocrinology”

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.

356 citations , December 1986 in “The journal of cell biology/The Journal of cell biology”

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

301 citations , February 2019 in “Nature Communications”

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

research Prospect of Stem Cell Conditioned Medium in Regenerative Medicine

298 citations , January 2014 in “BioMed Research International”

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives

233 citations , November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis

223 citations , September 2018 in “Rheumatology”

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells

research Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells

91 citations , July 2010 in “Tissue Engineering Part A”

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

research CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata

64 citations , July 2016 in “Journal of Immunology”

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

research Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells

64 citations , December 2012 in “Stem Cell Reviews and Reports”

Human hair follicle cells can be turned into stem cells similar to embryonic stem cells.

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