research Selected Abstracts
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
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research Hirsutism
Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.
research Androgen treatment in women
Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
research Genetic, hormonal and metabolic aspects of PCOS: an update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
research Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.
research The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle
CDP is crucial for lung and hair follicle cell development.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Defining hirsutism in Chinese women: a cross-sectional study
An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.
research Biomedical Applications of Layer‐by‐Layer Self‐Assembly for Cell Encapsulation: Current Status and Future Perspectives
Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
research Animal models for the study of fetal tissue repair
Understanding how fetal wounds heal could help improve healing in adults.
research Vitiligo
Vitiligo causes white skin patches and is linked to autoimmune issues.
research High prevalence of chronic thyroiditis in patients with polycystic ovary syndrome
People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.
research A novel purification procedure for keratin-associated proteins and keratin from human hair
A new method effectively separates keratin-associated proteins and keratin from human hair.
research Vitamin D-dependent rickets type II: extreme end organ resistance to 1,25-dihydroxy vitamin D3 in a patient without alopecia
A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
research A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive.
The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research Acorus calamus: a bio-reserve of medicinal values
*Acorus calamus* has many medicinal benefits but needs more safety research.
research Polycystic ovary syndrome (PCOS)
The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.
research p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss
The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
research Finasteride-induced secondary infertility associated with sperm DNA damage
Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
research Lichen planus and other cutaneous manifestations in chronic hepatitis C: pre- and post-interferon-based treatment prevalence vary in a cohort of patients from low hepatitis C virus endemic area
Skin problems like itching, dry skin, and hair loss are more common in hepatitis C patients after interferon treatment, but lichen planus is not linked to the infection.
research Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens
Some herbs show promise as antiandrogenic agents.
research PLASMA C19 STEROID SULPHATE LEVELS AND INDICES OF ANDROGEN BIOAVAILABILITY IN FEMALE PATTERN ANDROGENIC ALOPECIA
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
research Metabolic aspects of different phenotypes of polycystic ovary syndrome: Iranian PCOS Prevalence Study
The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
research Psychological aspects of hyperandrogenic states in late adolescent and young women
Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.
research Diagnostic approach to low‐renin hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.