research Select the most correct answers – multiple answers possible for questions 1–11
Medical practitioners need to understand basic statistics to properly evaluate clinical trials and avoid unethical designs.
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240-270 / 1000+ results research Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors
research Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens)
The assay effectively detects hormonal activity of certain chemicals.
research 50570 Irritation and sensitization potential of approved topical and transdermal delivery systems – A retrospective study
Generic topical and transdermal systems usually cause minimal irritation or sensitization.
research Use of a Healthcare Claims Database for Post-Marketing Safety Assessments of Eribulin in Japan: A Comparative Assessment with a Prospective Post-Marketing Surveillance Study
Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
research Spotlight Commentary: Importance of dose redefining in the process of drug repurposing
Redefining drug dosages is crucial when repurposing them for new uses.
research SARMS vs. anabolic steroids: comparative analysis of mechanisms, effects and health implications
research The comparative effectiveness of prescription and selected alternative therapies for pattern hair loss: protocol for a multiple treatment comparison meta-analysis
Prescription and alternative therapies for hair loss will be compared for effectiveness.
research SIMULTANEOUS ESTIMATION OF MINOXIDIL AND FINASTERIDE BY RP-HPLC IN PRESENCE OF SOY LECITHIN EXCIPIENT IN THE LOTION DOSAGE FORM
research Determination of finasteride in human serum by LC-MS/MS
A reliable method was developed to measure finasteride levels in human serum.
research Sensitive bromatometric assay methods for finasteride in pharmaceuticals
Three cost-effective methods accurately measure finasteride in pharmaceuticals, better than current techniques.
research A Dissolution Test for Finasteride in Immediate-Release Capsules
A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Minoxidil and finasteride determination by innovative high-performance liquid chromatography-ultraviolet approach for stability-indicating analysis
A new method accurately measures minoxidil and finasteride in medicines.
research The Model of an Ischemic Non-Healing Wound: Regeneration after Transplantation of a Living Skin Equivalent
Living Skin Equivalent transplantation helps heal ischemic non-healing wounds.
research Simultaneous spectrophotometric determination of finasteride and tadalafil in recently FDA approved Entadfi™ capsules
The methods accurately measure finasteride and tadalafil in Entadfi™ capsules for quality control.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
research 686 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging
QMSI is a valuable method for studying drug penetration in skin tissues.
research Drug–DrugCoamorphous System of Tadalafil andFinasteride for Enhanced Pharmaceutical Performance
A new combination of tadalafil and finasteride improves drug performance and stability.
research Correction to: Comparative Study to Evaluate Tolerability of Topical 5% Minoxidil Novel Formulation and Alcohol-Based Conventional Solutions in Treatment of Androgenetic Alopecia in Indian Men: Randomized Double-Blind Study
research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research 138 Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles
The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
research Uncertainty for HPLC Assay of Finasteride and Content Uniformity in Its Tablets
The method for measuring uncertainty in finasteride tablets is reliable.
research Investigation of drug partition property in artificial sebum
The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research PSS34 THE IMPACT OF POTENTIAL PILL SPLITTING ON GENERIC AND BRANDED FINASTERIDE UPTAKE
Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.
research UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS DETERMINATION OF FINASTERIDE AND TAMSULOSIN IN COMBINED DOSAGE FORM
Researchers developed a quick and accurate method to measure finasteride and tamsulosin in tablets.
research Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins
Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.
research Scientific Validation of "Clinically Proven" Claims: Compliance Focused and Global Regulatory Insights
"Clinically proven" claims require strict testing and adherence to guidelines for trust and authenticity.
research Aproximación a los metanálisis de comparación de múltiples tratamientos: una revisión de la literatura
Multiple treatment comparison meta-analyses help doctors make better decisions by comparing different interventions.