January 2025 in “Cosmetics” Exosomes could improve skin care, but more research is needed to confirm their safety and effectiveness.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
24 citations
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April 2005 in “The Journal of Dermatology” Putting ketoconazole on the skin can help mice grow hair.
January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.
510 citations
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August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
115 citations
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October 2003 in “Journal of Neuroscience” Aβ afferents do not sprout into the superficial spinal cord layers after nerve injury.
93 citations
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June 2011 in “Journal of Neuroscience” p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
80 citations
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June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
78 citations
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October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
71 citations
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May 1991 in “Clinical and Experimental Dermatology” Young men with male pattern baldness lose hair density over time without treatment.
44 citations
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June 2009 in “Biomaterials” Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.
43 citations
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August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
40 citations
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June 2013 in “Scientific Reports” A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
21 citations
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March 2025 in “Journal of Extracellular Vesicles” Hydrogels can enhance stem cell activity, but more research is needed to optimize their use.
20 citations
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July 2013 in “PLoS ONE” Targeting EGFR may help reduce hair loss from chemotherapy.
17 citations
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August 2023 in “Frontiers in Pharmacology” Asteraceae plants may help treat diabetes, but more research is needed.
14 citations
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April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
14 citations
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January 2009 in “Experimental Dermatology” Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
13 citations
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December 2019 in “Nutrients” An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
12 citations
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August 2019 in “BMC Medical Genetics” Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
11 citations
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October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
11 citations
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January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
10 citations
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January 2024 in “Polymer Chemistry” Lipid–polymer hybrid nanoparticles can improve genome editing delivery and outcomes.
9 citations
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September 2015 in “Reproductive Biomedicine Online” Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.
7 citations
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December 2022 in “Frontiers in Bioengineering and Biotechnology” Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
7 citations
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January 2017 in “Journal of Clinical Biochemistry and Nutrition” Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.
6 citations
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January 2015 in “Biochemical Society Transactions” The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.