research The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin
S-Methylmethionine sulfonium can protect skin from UVB damage.
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330-360 / 1000+ resultsresearch Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Development of Heritable Melanoma in Transgenic Mice
The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
research Epidermal cells: methods and protocols
research MELATONIN AND THE SKIN:FROM FROG TO HUMAN
Melatonin can affect skin color, treat skin conditions, and may help with skin cancer.
research Editorial: Mechanisms and novel treatments of pigmentary disorders and skin regeneration
New treatments and drugs show promise for improving skin pigmentation and regeneration.
research Subclinical speckled perifollicular melanosis of the scalp.
The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
research Desmoplastic melanoma presenting as primary alopecia neoplastica: a report of two cases
Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Dermoscopy of Thick Scalp Melanoma: Is It Always an Easy Diagnosis?
Thick scalp melanoma can be hard to diagnose because it often looks like other skin conditions.
research Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation
Meloside A may help protect hair cells from damage linked to hair loss.
research The murine hair follicle is a melatonin target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Marine-Biomass-Derived Melanin–Chitosan Composites as Natural Black Hair Colorants: Charge Reversal and Electrostatic Deposition Mechanism
A natural hair dye from cuttlefish ink and chitosan effectively colors hair black without harmful chemicals.
research Photochemical alterations in human hair. I. Artificial irradiation and investigations of hair proteins
Melanin in black hair protects it from sun damage better than light-brown hair.
research 1379 Cell of origin contributes to the melanoma diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research An exclusive review of melatonin effects on mammalian melanocytes and melanoma
Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
research The ‘melanocyte-keratin’ mystery revisited: neither normal human epidermal nor hair follicle melanocytes express keratin 16 or keratin 6in situ
Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.
research Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage
Activating β-catenin increases melanocytes and decreases Schwann cells.
research Engineering a New Mouse Model for Vitiligo
A new mouse model for vitiligo helps study immune responses and potential treatments.
research Synergy of understanding dermatologic disease and epidermal biology
Advancements in skin and hair biology improve dermatology care and cosmetic treatments.
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin
POMC-derived peptides are important for skin functions like immune response and stress management.
research 1339 Casein kinase 1 inhibition in keratinocytes enhances the migration of melanocyte precursors in the hair follicle via KitL/c-Kit signaling pathway
Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
research Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous?
KIT's role in skin cells is not entirely independent, as other cells can influence its function.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
3D skin models better mimic human skin and melanoma progression than older methods.
research Dual aspects of B cells in tumor immunity; B cells are capable of positive and negative regulation for tumor immunity against B16 melanoma
B cells can both help and hinder the body's defense against melanoma.
research Mechanism of action and promising clinical application of melatonin from a dermatological perspective
Melatonin may help treat skin conditions.
research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research Downregulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors
Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.