research The BJUI 's clinical trials initiative
The BJUI supports clinical trials as key for unbiased medical evidence and works to enhance their design, reporting, and discussion.
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research Evaluation of noninvasive biospecimens for transcriptome studies
Hair follicles and urine cell pellets are promising for transcriptome studies due to consistent quality and useful expression profiles.
research America - A Diversity of Life Styles.
The drug showed promise in treating renal cell carcinoma with manageable side effects.
research Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays
The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.
research AnnoPharma: Detection of substances responsible of ADR by annotating and extracting information from MEDLINE abstracts
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.
research Neonatal screening in Sweden and disease-causing variants in phenylketonuria, galactosaemia and biotinidase deficiency
The Swedish neonatal screening program effectively detects PKU, galactosaemia, and biotinidase deficiency with low false positives.
research Using a capture–recapture method to assess the frequency of adverse drug reactions in a French university hospital
The study found that combining different databases gives a better estimate of drug side effects in hospitals.
research Evaluation of Patellar Tendon Structural Changes following Biological Treatments: Secondary Analysis of Double-Blinded Clinical Trial of Bone Marrow Mesenchymal Stromal Cells and Leukocyte-Poor Platelet-Rich Plasma
Bone marrow cells improved tendon health better than platelet-rich plasma.
research Developing Humanized Animal Models with Transplantable Human iPSC-Derived Cells
Humanized animal models using human stem cells can improve disease research and drug testing.
research Biochemical and Histopathological evaluation of prostatic tissue under effect of Pterostilbene in benign prostatic hyperplasia rat model
Pterostilbene significantly reduces prostate enlargement and has strong antioxidant effects.
research When two plus two must not equal four
Regulatory challenges make developing combination therapies in urology difficult and costly.
research Sensitive bromatometric assay methods for finasteride in pharmaceuticals
Three cost-effective methods accurately measure finasteride in pharmaceuticals, better than current techniques.
research Cardiac biopsy in myocarditis
Some people have a genetic variation that makes them less effective at breaking down drugs.
research Utilização de plaquetas e de produtos derivados de plaquetas humanas em terapias avançadas
Platelets and their derivatives, like PRP, can help tissue regeneration, but need standardized safety protocols.
research Recent European legal developments on second medical uses and dosage regimes
European patent law now allows patents for new uses and dosages of known drugs, but protection scope is unclear.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Advanced chemical imaging and comparison of human and porcine hair follicles for drug delivery by confocal Raman microscopy
Confocal Raman microscopy can effectively study drug delivery in hair follicles using pig ear models.
research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
research Preclinical Development and Phase I Study of ZSYY001 , a Polymeric Micellar Paclitaxel for Advanced Solid Tumor
ZSYY001 is safe, well-tolerated, and shows promise for treating advanced solid tumors.
research 41261 Identification of Demographic and Clinical Features Associated with Multi-Biologic Failure in the CorEvitas Psoriasis Registry
Certain factors like being female, having high cholesterol, using Medicaid, and previous non-biologic treatments increase the risk of multiple biologic failures in psoriasis patients.
research Quality issues identified in systematic reviews on platelet‐rich plasma therapy for pattern hair loss—A method study
Systematic reviews on platelet-rich plasma therapy for hair loss have many quality issues.
research An Overview of the Developments in Platelet-rich Plasma Research and Its Clinical Use
PRP shows promise in musculoskeletal rehabilitation but needs standardized reporting for better outcomes.
research Basic research in biostimulation
Low-output laser irradiation can stimulate or inhibit biological processes depending on the dose.
research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
The method effectively measures drug impact on DHT levels in prostate treatments.
research Prodrugs of butyric acid from bench to bedside: Synthetic design, mechanisms of action, and clinical applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Farmácia Sanches - Leiria e nos Serviços Farmacêuticos do Hospital Lusíadas - Porto
Pharmacists play a crucial role in health literacy and patient care.
research Phytochemical studies on traditional herbal medicines based on the ethnopharmacological information obtained by field studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research Green Technologies in the Generic Pharmaceutical Industry
Green technologies can make the pharmaceutical industry more sustainable by reducing waste.
research Photobiomodulation or low‐level laser therapy
Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.
research Preparing regenerative therapies for clinical application: proposals for responsible translation
The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.