March 1993 in “Neuroscience letters” Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
October 2023 in “International Journal of Cosmetic Science” WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
74 citations
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July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
1 citations
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February 2022 in “Journal of the American Academy of Dermatology” Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.
13 citations
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January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
8 citations
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June 1981 in “Clinica Chimica Acta” February 1994 in “Neuroscience letters” People need different amounts of biotin based on age and it's important for health, with many foods providing enough.
September 1989 in “Neuroscience letters” People need different amounts of biotin based on age, and not getting enough can cause health problems.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” The best biotin hair tonic formula has 20% span 80, 9.47% tween 80, and 5% PEG 400.
Biotin boosts wool growth and follicle health in sheep.
26 citations
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May 1984 in “Journal of Parenteral and Enteral Nutrition” Biotin supplements restored hair and resolved symptoms in a woman with biotin deficiency.
3 citations
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April 2015 in “Current problems in dermatology” A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.
January 1999 in “Proceedings of the British Society of Animal Science” Biotin deficiency may harm hair follicle health and growth in Angora goats.
1 citations
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January 1999 in “Proceedings of the British Society of Animal Science” Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
January 2000 in “Europe PMC (PubMed Central)”
10 citations
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September 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
4 citations
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January 1986 in “PubMed” Serum biotin levels can indicate biotin deficiency in sows.
3 citations
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January 1966 in “PubMed”
May 2025 in “Health Science Reports” Serum WS Biotin significantly reduces hair shedding and improves hair thickness.
January 1998 in “Proceedings of the British Society of Animal Science” Biotin supports cell growth and DNA synthesis in Angora goat hair follicles.
January 1998 in “Proceedings of the British Society of Animal Science” Biotin supports cell growth and DNA synthesis in Angora goat hair follicles.
May 2022 in “Endocrine practice” High-dose biotin can cause false thyroid test results; stop taking biotin two days before testing to avoid errors.
Biotin does not significantly help with hair growth.
49 citations
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April 2007 in “Pediatric Dermatology” Biotin improved hair appearance in uncombable hair syndrome but didn't change hair structure.
September 2024 in “Meditsinskiy sovet = Medical Council” Biotin effectively treats hair loss, skin, and nail issues without overdose risk.
August 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
6 citations
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January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
May 2022 in “International Journal of Biochemistry Research and Review” Plant-based biotin from SesZenBioTM could be twice as effective as synthetic biotin for hair care.
May 2010 in “Europe PMC (PubMed Central)” Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.