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research Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle

3 citations , March 2012 in “Arab Journal of Urology”

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

research Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats"

January 2024

research Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats"

September 2023

research Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase

25 citations , August 2015 in “Molecules”

Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.

research Effectiveness and safety of finasteride in male chronic pelvic pain syndrome

2 citations , August 2011 in “Cochrane Database of Systematic Reviews”

research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies

4 citations , May 2023 in “Cells”

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

research 5alpha-reductase 2 inhibition impairs brain defeminization of male rats: Reproductive aspects

26 citations , September 2005 in “Pharmacology Biochemistry and Behavior”

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation

53 citations , October 2011 in “Psychoneuroendocrinology”

Finasteride may help improve certain brain function issues linked to dopamine.

research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases

December 2023 in “Biointerface Research in Applied Chemistry”

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

research Alfuzosin/finasteride

May 2023 in “Reactions Weekly”

research Alfuzosin/finasteride

January 2013 in “Reactions Weekly”

research Glibenclamide reverses cromakalim-induced anti-ischemic effect in conscious rabbits

1 citations , May 1992 in “Pharmacological Research”

research Treatment of actinic cheilitis with ingenol mebutate gel: Experience in four patients

May 2015 in “Journal of The American Academy of Dermatology”

Finasteride for hair loss in young men increases the risk of sexual dysfunction.

Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia

research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia

January 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.

research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity

65 citations , October 2008 in “Journal of Neuroendocrinology”

(1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production

research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production

14 citations , August 2007 in “Bioorganic & Medicinal Chemistry Letters”

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands

research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands

November 2021 in “Pharmaceutical Sciences”

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome

July 2024 in “Journal of Investigative Dermatology”

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

research Dutasteride/finasteride

April 2022 in “Reactions Weekly”

research Preformulation studies of finasteride to design matrix systems for topical delivery

14 citations , August 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process

13 citations , May 2011 in “Bioorganic & Medicinal Chemistry”

Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.

research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia

January 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.

research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor

1 citations , August 2021 in “Journal of Investigative Dermatology”

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

Proxalutamide Reduces Hospitalization Rate in Mild-to-Moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Trial

research Proxalutamide (GT0918) Reduces the Rate of Hospitalization in mild-to-moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Two-Arm Parallel Trial

5 citations , July 2021 in “medRxiv (Cold Spring Harbor Laboratory)”

Proxalutamide significantly lowered hospitalization rates in women with mild-to-moderate COVID-19.

research Response to “Improvement of female pattern hair loss with bicalutamide: a time-dependent process”

August 2025 in “JAAD International”

Bicalutamide may take longer to work for female hair loss, and higher doses might be needed.

Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

research Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1<i>H</i>-imidazol-5-yl]-1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

6 citations , January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin”

A new compound shows promise as a topical treatment for hair loss.

research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies

August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

research Decision letter: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

January 2017

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

research Bicalutamide improves minoxidil-induced hypertrichosis in female pattern hair loss: A retrospective review of 35 patients

4 citations , November 2021 in “Journal of The American Academy of Dermatology”

Bicalutamide may reduce unwanted hair growth caused by minoxidil in women with hair loss.

research Highlights from JAAD Reviews: August 2025—Bicalutamide for female hair loss

May 2025 in “Journal of the American Academy of Dermatology”

Bicalutamide shows promise for treating female hair loss.

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