71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
69 citations
,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
60 citations
,
April 2003 in “Human Reproduction” Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.
53 citations
,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.
53 citations
,
December 2015 in “JAMA Dermatology” Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
53 citations
,
January 2012 in “Fertility and Sterility” Women with PCOS are more likely to have sleep apnea, mainly if they are obese.
51 citations
,
March 2004 in “Hormone and Metabolic Research” Women with Polycystic Ovary Syndrome have higher levels of the hormone ghrelin, which may be linked to the cause of the condition.
46 citations
,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
45 citations
,
January 2013 in “Journal of Human Reproductive Sciences” Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
42 citations
,
July 2017 in “Scientific Reports” Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
38 citations
,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
37 citations
,
March 2014 in “Journal of Trace Elements in Medicine and Biology” Lower hair zinc and copper levels found in Turkish males with hair loss; higher BMI linked to less hair zinc.
37 citations
,
April 2013 in “Plastic and Reconstructive Surgery” Genetic and environmental factors, like smoking and exercise, affect male hair loss.
35 citations
,
July 2015 in “Journal of Affective Disorders” Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.
33 citations
,
November 2012 in “Journal of The American Academy of Dermatology” FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.
31 citations
,
January 2014 in “Clinical Endocrinology” The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
28 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
27 citations
,
September 2017 in “Acta dermato-venereologica” Adults with certain skin conditions may have higher levels of inflammation in their body.
23 citations
,
January 2016 in “Journal of Nanjing Medical University” Overweight women with PCOS are more likely to have excess male hormones.
21 citations
,
September 2021 in “Fertility and Sterility” A blood test level of 3.2 ng/mL of Antimüllerian hormone is good for identifying polycystic ovarian morphology in European women aged 25–45.
21 citations
,
May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.
21 citations
,
August 2014 in “Gynecological Endocrinology” Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
20 citations
,
August 2022 in “Archives of Medical Science” The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
20 citations
,
September 2020 in “International journal of computer applications” The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.
20 citations
,
October 2008 in “European journal of endocrinology” Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
18 citations
,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
18 citations
,
July 2010 in “Expert Review of Endocrinology & Metabolism” The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
17 citations
,
July 2015 in “Biomolecules and Biomedicine” High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.