71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
105 citations
,
June 2010 in “The journal of sexual medicine” Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.
343 citations
,
October 2015 in “Endocrine Practice” The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
28 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
8 citations
,
March 2008 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.
6 citations
,
September 1998 in “The Journal of The British Menopause Society” Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
May 2025 in “Anatolian journal of obstetrics and gynecology research.” Androgens affect many aspects of female health, and more research is needed to understand their roles and treatment potential.
December 2024 in “Frontiers in Neurology” Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
42 citations
,
May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
September 2012 in “African Journal of Urology” Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
29 citations
,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
January 2017 in “NASA Technical Reports Server (NASA)” Early changes in skin gene expression can predict later bone mass loss after radiation exposure.
3 citations
,
April 2016 in “Clinical and Experimental Obstetrics & Gynecology” Young female athletes should be informed about health risks like menstrual issues and bone problems from excessive sports.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
222 citations
,
August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
11 citations
,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
June 2019 in “Medicine and science in sports and exercise” The runner's bone injuries were linked to untreated Celiac Disease and low energy availability affecting her bone density.
14 citations
,
February 2013 in “PubMed” Patients treated with long-term intralesional corticosteroids for alopecia areata should be monitored for bone density changes and advised on osteoporosis prevention.
45 citations
,
February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
July 2020 in “Research Square (Research Square)” Obesity and certain hormone levels can lead to advanced bone age in young girls with early breast development.
July 2020 in “Research Square (Research Square)” Higher BMI, IGF-1, and DHEAS levels are linked to advanced bone age in young Chinese girls with early breast development.
72 citations
,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
October 2008 in “DOAJ (DOAJ: Directory of Open Access Journals)” A 20-month-old girl had a rare adrenal tumor removed successfully, with no recurrence for 10 years.