March 2024 in “Frontiers in genetics” Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
51 citations
,
March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
24 citations
,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
2 citations
,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
2 citations
,
January 2008 in “Elsevier eBooks” Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
November 2025 in “Frontiers in Immunology” Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.
January 2008 in “Durham e-Theses (Durham University)” Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
59 citations
,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
2 citations
,
May 2021 in “Bioengineering” Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.
26 citations
,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
9 citations
,
April 2018 in “Journal of trace elements in medicine and biology” Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
252 citations
,
February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
27 citations
,
January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
103 citations
,
March 2011 in “PLoS Biology” Birds can lose neck feathers due to a genetic change that increases a gene's activity, helping them adapt to heat.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
20 citations
,
July 2013 in “European Journal of Oral Sciences” A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.
7 citations
,
September 2017 in “Scientific Reports” Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
3 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
92 citations
,
December 2012 in “Current opinion in genetics & development” Turing patterns are now recognized as important in developmental biology.
12 citations
,
December 2020 in “Archives animal breeding/Archiv für Tierzucht” EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.
3 citations
,
October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.