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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The Rotterdam Study aims to understand various diseases in older adults.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Bioengineered tooth germ can restore whole teeth in dogs.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Iron deficiency may contribute to hair loss.

Plant compounds may offer a promising alternative for cancer treatment.

Genetic differences affect COVID-19 severity and treatment development.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Custom-designed implants effectively repaired skull damage in most soldiers injured in combat.

Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Obesity and lifestyle strongly affect heart aging.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Blocking certain fat production can reverse skin inflammation and hair loss.

New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.

Men are more affected by COVID-19 due to differences in immune responses and protein expression.

PEVs effectively deliver minoxidil through skin.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.