research A woman with iatrogenic androgenetic alopecia responding to finasteride
EF and PXE not closely related.
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510-540 / 1000+ results research Dapsone versus topical immunotherapy in alopecia areata
Topical immunotherapy is more effective than dapsone for treating severe alopecia areata.
research Response to minoxidil in severe alopecia areata correlates with T lymphocyte stimulation
Increased T cell activity may predict hair regrowth success with minoxidil in severe alopecia areata.
research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP3‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles
Caffeine may help reduce stress-induced hair loss.
research Is methotrexate an effective and safe treatment for maintaining hair regrowth in people with alopecia totalis? A Critically Appraised Topic
Methotrexate's effectiveness for maintaining hair regrowth in alopecia totalis is unclear due to limited and biased data.
research Identification of factors contributing to phenotypic divergence via quantitative image analyses of autosomal recessive woolly hair/hypotrichosis with homozygous c.736T>ALIPH mutation
Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.
research Comparative transcriptome profiling provides new insights into mechanisms of androgenetic alopecia progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Childhood epidermolysis bullosa acquisita during squaric acid dibutyl ester immunotherapy for alopecia areata
A 6-year-old boy's skin condition improved after stopping a specific treatment and starting new medications.
research Understanding breakage in curly hair
Curly hair breaks due to mechanical damage and environmental factors, not chemical makeup, and needs ongoing care to prevent breakage.
research Vitiligo: an evidence-based update. Report of the 13th Evidence Based Update Meeting, 23 May 2013, Loughborough, U.K.
The meeting concluded with optimism about increasing research and better management of vitiligo.
research Medicolegal aspects of doping in football
Doping in football faces legal challenges with testosterone limits, hair loss treatments, and recreational drug use.
research Trichoblastoma with sebaceous and sweat gland differentiation
A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
research The induction by topical minoxidil of increased fenestration in the perifollicular capillary wall
Minoxidil increased small openings in blood vessel walls near growing hair in rats.
research Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research The effect of minoxidil analogues and metabolites on the contraction of collagen lattices by human skin fibroblasts
research Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth
Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.
research Identification of compound heterozygous mutations in AP1B1 leading to the newly described recessive keratitis–ichthyosis–deafness (KIDAR) syndrome
Mutations in the AP1B1 gene cause a new syndrome with skin, hearing, and developmental issues.
research Use of an alternative method to evaluate erythema severity in a clinical trial: difference in vehicle response with evaluation of baseline and postdose photographs for effect of oxymetazoline cream 1·0% for persistent erythema of rosacea in a phase IV study
Oxymetazoline cream 1.0% effectively reduces rosacea redness, and using baseline photos improves assessment accuracy.
research Can UK undergraduate dental programmes provide training in non-surgical facial aesthetics?
Most UK dental schools don't teach non-surgical facial aesthetics, but dentists have a good knowledge base to provide these services.
research Novel adenosine triphosphate (ATP)-binding cassette, subfamily A, member 12 (ABCA12) mutations associated with congenital ichthyosiform erythroderma
New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.
research Identical p53 gene mutation in malignant proliferating trichilemmal tumour of the scalp and small cell carcinoma of the common bile duct: the necessity for therapeutic caution?
Identical p53 gene mutations in different cancers suggest the need for careful treatment.
research Idiopathic hirsutism: excessive bodily and facial hair in women
Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.
research Pattern of expression of c-Myc, Max and Bin1 in human anagen hair follicles
c-Myc, Max, and Bin1 help hair follicle cells mature and die.
research Serum-free culture of wool follicles: effects of nutrients, growth factors and hormones
Wool follicles grew fibres for 8-10 days in a serum-free culture, influenced by calcium, glucose, amino acids, and insulin.
research Expression of extracellular matrix in hair follicle mesenchyme in alopecia areata
Alopecia areata may involve disrupted mesenchymal function in hair follicles.
research An inherited nail dystrophy principally affecting the great toenails
The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
research Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin.
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research Hirsutism and virilisation.
Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.
research Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles
The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.
research Blood MUC-18/MCAM expression in patients with melanoma: a suitable marker of poor outcome
High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.