research Immunochemical studies on blood group A substance from human hair
Human hair contains a substance that shows blood group A activity.
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research High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching
New method detects finasteride in plasma quickly and accurately without clean-up.
research Testosterone enhances expression and functional activity of epithelial sodium channel (ENaC), cystic fibrosis transmembrane regulator (CFTR) and sodium hydrogen exchanger (NHE) in vas deferens of sex-steroid deficient male rats
Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
research The effect of long‐chain monoenes on prostaglandin E2 synthesis by rat skin
High levels of certain fats in rapeseed oil can reduce the skin's ability to produce prostaglandin E2 and cause hair loss and skin issues in rats.
research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
research Determination of finasteride by HPLC-MS and study its pharmacokinetics
A new method accurately measures finasteride levels in blood and shows how the body processes it.
research Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
Blocking progesterone metabolism can cause depression-like behavior in mice.
research Emulsifying Properties of α-Chitin Nanofibrils Prepared by Aqueous Counter Collision
Chitin nanofibrils are better at stabilizing oil droplets in emulsions than cellulose nanofibrils.
research 胃切除・腸切除術後の退院指導-パンフレットを使用して-
Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research Phosphofructokinase (Pfk) Regulation of Glycolysis in Skin
research Apparent Hyperandrogenemia Due to Immunoassay Interference Resolved by Liquid Chromatography–Tandem Mass Spectrometry
False high testosterone levels were corrected using a more accurate test.
research Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4-lsomerase in Human Adrenals and Gonads
Human adrenals and gonads have a unique enzyme for steroid hormone production.
research Effect of human hair keratin on the function of rat liver,renal,heart and hematology profile
Hair keratin doesn't significantly affect rat organ function but may help detect early rejection through blood changes.
research Testosterone, cytochrome P450, and cardiac hypertrophy
Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Finasteride/testosterone
research Psoriatic onychopachydermoperiostitis: improvement with etanercept
Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.
research Serum granulysin as a possible key marker of the activity of alopecia areata
Serum granulysin levels can indicate the activity and prognosis of alopecia areata.
research Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.
research Chromatographic Methods for the Determination of Aminexil, Pyridoxine, and Niacinamide in a Novel Cosmetic Hair Preparation
Two new methods accurately measure Aminexil, Pyridoxine, and Niacinamide in hair products.
research Mice Expressing a Mutant Krt75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita
research Enzymatic Crosslinking of Amino Acids Improves the Repair Effect of Keratin on Hair Fibre
Using enzymes to link proteins makes hair repair treatments more effective and long-lasting.
research Biotinidase deficiency: a survey of 10 cases.
Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
research Editorial Comment
Self-management can help improve symptoms of benign prostatic hyperplasia.
research Studies on synthesis of finasteride
The new method for making finasteride is cheaper and gives a higher yield.
research Granzyme B in skin aging, injury and repair
Granzyme B accelerates skin aging and impairs healing by breaking down important skin components.
research Simultaneous determination of multi-class active pharmaceutical ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
research Quantitative and qualitative analysis of individual experiences post botulinum toxin injection ‐ United Kingdom Survey
Most UK survey participants had negative side effects from botulinum toxin injections, with many not fully recovering physically, emotionally, or financially.
research Cloning of the human phenol sulfotransferase gene family: three genes implicated in the metabolism of catecholamines, thyroid hormones and drugs
Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.