Search

everythinglearnresearchcommunity

for

Search:↓

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride's molecular and crystal structures help develop new drug formulations.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

New steroids were effective in blocking male hormone receptors in hamster prostates.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.