38 citations
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September 2004 in “Journal of Autoimmunity” Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.
143 citations
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January 2007 in “The American Journal of Human Genetics” Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
4 citations
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December 2016 in “Medical lasers” Lasers can be effective for treating hair loss from alopecia areata.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
January 2024 in “Updates in clinical dermatology” Photobiomodulation effectively stimulates hair growth and reduces hair loss.
January 2018 in “International journal for pharmaceutical research scholars” Meniran extract hair tonic may stimulate hair growth in rats, with the version containing 1% menthol being more effective.
253 citations
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December 2007 in “Journal of Investigative Dermatology” Hair follicles prevent NK cell attacks to avoid hair loss.
55 citations
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October 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
21 citations
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December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
19 citations
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August 2017 in “American journal of clinical dermatology” Hepatitis B virus exposure may be linked to increased risk of alopecia areata.
7 citations
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December 2019 in “Experimental and Therapeutic Medicine” WNT10B affects hair growth by altering gene activity in hair cells.
1 citations
,
June 2023 in “Journal of Cosmetic Dermatology” Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
September 2025 in “Lasers in Medical Science”
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
79 citations
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December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
61 citations
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September 2010 in “Journal of Dermatological Science” Stress hormones and autoimmune reactions can cause hair loss.
26 citations
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December 2020 in “Photodermatology Photoimmunology & Photomedicine” Photobiomodulation can improve hair density and thickness, but it's costly and needs more research.
18 citations
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August 2012 in “Chinese journal of integrative medicine/Chinese Journal of Integrative Medicine” Both treatments for alopecia areata are equally effective and safe.
4 citations
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December 2021 in “Applied sciences” Micro-needling with low-level light therapy effectively increases hair growth in people with mild to moderate hair loss.
1 citations
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April 2024 in “Journal of Autoimmunity” Interleukin-15 can help hair growth and protect hair follicles.
June 2025 in “Pharmacon Jurnal Farmasi Indonesia” Mangkokan leaves may help hair growth and health.
Minoxidil and finasteride are the only FDA-approved treatments for hair loss caused by genetic and hormonal factors, but their effectiveness is often doubted, indicating a need for new treatments.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
134 citations
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July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
106 citations
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January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
64 citations
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October 2020 in “Journal of lasers in medical sciences” Low-level laser therapy shows promise but needs more research for improvement.
63 citations
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July 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” JAK inhibitors can effectively reverse hair loss in people with alopecia areata.
57 citations
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August 2023 in “American Journal of Clinical Dermatology” JAK inhibitors and platelet-rich plasma show promise for treating alopecia areata.